Chonprasertsuk Soonthorn, Vilaichone Ratha-Korn
Gastroenterology unit, Department of Medicine, Thammasat University Hospital, Pathumthani, Thailand.
Jpn J Clin Oncol. 2017 Apr 1;47(4):294-297. doi: 10.1093/jjco/hyw197.
Hepatocellular carcinoma (HCC) is the most frequent type of malignant liver tumor in Thailand. The high incidence rate of HCC reflects from chronic HBV infection in this endemic area. Some patients are asymptomatic at presentation whereas many of them presented at advanced stage of HCC with limited treatment options and grave outcome. The Barcelona Clinic Liver Cancer (BCLC) staging system and management allocation for HCC is widely accepted and used in many international guidelines including Thailand. Curative treatment is expected in early stage of HCC while palliative treatment, combination treatment and best supportive care are offered to advanced stage of HCC. The most effective strategy to prevent the development of HCC is prevention of HBV vertical transmission and treatment HBV or HCV infection. The purpose of this article is to update information of HCC in Thailand including epidemiology, diagnosis, clinical manifestation, and treatment.
肝细胞癌（HCC）是泰国最常见的恶性肝肿瘤类型。HCC的高发病率反映了该流行地区慢性乙肝病毒感染的情况。一些患者在就诊时无症状，而许多患者在HCC晚期就诊，治疗选择有限且预后严重。巴塞罗那临床肝癌（BCLC）分期系统及HCC的治疗分配在包括泰国在内的许多国际指南中被广泛接受和使用。HCC早期有望进行根治性治疗，而晚期HCC则提供姑息治疗、联合治疗和最佳支持治疗。预防HCC发生的最有效策略是预防乙肝病毒垂直传播以及治疗乙肝或丙肝感染。本文的目的是更新泰国HCC的相关信息，包括流行病学、诊断、临床表现和治疗。
