Ahmadi Rahimeh, Ziaei Saeideh, Parsay Sosan
Department of Midwifery and Reproductive Health, Faculty of Medical Science, Tarbiat Modares University, Tehran, Iran.
Int J Fertil Steril. 2017 Jan-Mar;10(4):337-342. doi: 10.22074/ijfs.2016.4577. Epub 2016 Nov 1.
Spontaneous abortion is the most common adverse pregnancy outcome. We aimed to investigate a possible link between nutrient deficiencies and the risk of spontaneous abortion.
This case-control study included the case group (n=331) experiencing a spontaneous abortion before 14 weeks of pregnancy and the control group (n=331) who were healthy pregnant women over 14 weeks of pregnancy. The participants filled out Food Frequency Questionnaire (FFQ), in which they reported their frequency of consumption for a given serving of each food item during the past three months, on a daily, weekly or monthly basis. The reported frequency for each food item was converted to a daily intake. Then, consumption of nutrients was compared between the two groups.
There are significant differences between the two groups regarding consumed servings/day of vegetables, bread and cereal, meat, poultry, fish, eggs, beans, fats, oils and dairy products (P=0.012, P<0.001, P=0.004, P<0.001, P=0.019, respectively). There are significant differences between the two groups in all micronutrient including folic acid, iron, vitamin C, vitamin B6, vitamin B12 and zinc (P<0.001).
Poor nutrientions may be correlated with increased risk of spontaneous abortion.
自然流产是最常见的不良妊娠结局。我们旨在研究营养缺乏与自然流产风险之间的可能联系。
这项病例对照研究包括妊娠14周前发生自然流产的病例组（n = 331）和妊娠14周以上的健康孕妇对照组（n = 331）。参与者填写了食物频率问卷（FFQ），其中他们报告了过去三个月中每种食物给定份量的食用频率，以每日、每周或每月为基础。每种食物报告的频率转换为每日摄入量。然后，比较两组之间的营养素摄入量。
两组在蔬菜、面包和谷物、肉类、家禽、鱼类、蛋类、豆类、脂肪、油类和乳制品的每日食用份量方面存在显著差异（分别为P = 0.012、P < 0.001、P = 0.004、P < 0.001、P = 0.019）。两组在所有微量营养素方面存在显著差异，包括叶酸、铁、维生素C、维生素B6、维生素B12和锌（P < 0.001）。
营养状况不佳可能与自然流产风险增加相关。
