Khamineh Yasaman, Ghiasvand Mahsa, Panahi-Alanagh Sanaz, Rastegarmand Parisa, Zolghadri Samaneh, Stanek Agata
Department of Animal Sciences and Marine Biology, Faculty of Life Sciences and Biotechnology, Shahid Beheshti University, Tehran 1983969411, Iran.
Department of Stem Cells and Developmental Biology, Cell Science Research Centre, Royan Institute for Stem Cell Biology and Technology, Academic Center for Education, Culture and Research (ACECR), Tehran 3365166571, Iran.
Nutrients. 2025 Mar 24;17(7):1118. doi: 10.3390/nu17071118.
Lifestyle, nutrition, and metabolic status are central to maintaining women's reproductive health. With the rising prevalence of infertility, the need for effective strategies to preserve and enhance women's reproductive well-being has become increasingly urgent. Quercetin, a plant-derived polyphenol, has attracted growing interest for its potential to support reproductive health, regulate the hormonal balance, and improve fertility. This narrative review examines Quercetin's role in women's reproductive health and delineates its possible mechanisms of action in female reproductive system disorders, including polycystic ovary syndrome, recurrent miscarriage, and cervical, ovarian, and endometrial cancer (EC). By highlighting the biological pathways through which quercetin may exert its effects, this article underscores the need for further research and clinical trials to validate its therapeutic potential and its applications as a bioactive compound in foods aimed at enhancing women's reproductive health.
生活方式、营养和代谢状况是维持女性生殖健康的核心。随着不孕症患病率的上升，制定有效策略来维护和提升女性生殖健康的需求变得越来越迫切。槲皮素是一种植物源多酚，因其在支持生殖健康、调节激素平衡和提高生育能力方面的潜力而受到越来越多的关注。这篇叙述性综述探讨了槲皮素在女性生殖健康中的作用，并阐述了其在女性生殖系统疾病（包括多囊卵巢综合征、复发性流产以及宫颈癌、卵巢癌和子宫内膜癌）中可能的作用机制。通过强调槲皮素可能发挥作用的生物学途径，本文强调了进一步研究和临床试验的必要性，以验证其治疗潜力以及作为一种生物活性化合物在旨在增强女性生殖健康的食品中的应用。
