Herbert Peter, Hayes Lawrence D, Sculthorpe Nicholas, Grace Fergal M
a School of Sport, Health and Outdoor Education, Trinity Saint David, University of Wales , Carmarthen , UK.
b Active Ageing Research Group, Department of Medical and Sport Sciences, University of Cumbria , Lancaster , UK.
Aging Male. 2017 Mar;20(1):54-59. doi: 10.1080/13685538.2016.1260108. Epub 2016 Dec 31.
The aim of this investigation was to examine the impact high-intensity interval training (HIIT) on serum insulin-like growth factor-I (IGF-I) in active compared with sedentary aging men.
22 lifetime sedentary (SED; 62 ± 2 years) and 17 masters' athletes (LEX; 60 ± 5 years) were recruited to the study. As HIIT requires preconditioning exercise in sedentary cohorts, the study required three assessment phases; enrollment (phase A), following preconditioning exercise (phase B), and post-HIIT (phase C). Serum IGF-I was determined by electrochemiluminescent immunoassay.
IGF-I was higher in LEX compared to SED at baseline (p = 0.007, Cohen's d = 0.91), and phase B (p = 0.083, Cohen's d = 0.59), with only a small difference at C (p = 0.291, Cohen's d = 0.35). SED experienced a small increase in IGF-I following preconditioning from 13.1 ± 4.7 to 14.2 ± 6.0 μg·dl (p = 0.376, Cohen's d = 0.22), followed by a larger increase post-HIIT (16.9 ± 4.4 μg·dl), which was significantly elevated compared with baseline (p = 0.002, Cohen's d = 0.85), and post-preconditioning (p = 0.005, Cohen's d = 0.51). LEX experienced a trivial changes in IGF-I from A to B (18.2 ± 6.4 to 17.2 ± 3.7 μg·dl [p = 0.538, Cohen's d = 0.19]), and a small change post-HIIT (18.4 ± 4.1 μg·dl [p = 0.283, Cohen's d = 0.31]). Small increases were observed in fat-free mass in both groups following HIIT (p < 0.05, Cohen's d = 0.32-0.45).
In conclusion, HIIT with preconditioning exercise abrogates the age associated difference in IGF-I between SED and LEX, and induces small improvements in fat-free mass in both SED and LEX.
本研究旨在探讨高强度间歇训练（HIIT）对活跃的老年男性与久坐不动的老年男性血清胰岛素样生长因子-I（IGF-I）的影响。
招募了22名终生久坐不动的男性（SED；62±2岁）和17名老年运动员（LEX；60±5岁）参与本研究。由于HIIT需要对久坐不动的人群进行预处理运动，因此该研究需要三个评估阶段：入组（A阶段）、预处理运动后（B阶段）和HIIT后（C阶段）。通过电化学发光免疫分析法测定血清IGF-I。
在基线时（p = 0.007，科恩d值 = 0.91）以及B阶段（p = 0.083，科恩d值 = 0.59），LEX组的IGF-I高于SED组，而在C阶段两组差异较小（p = 0.291，科恩d值 = 0.35）。SED组在预处理后IGF-I略有增加，从13.1±4.7升至14.2±6.0μg·dl（p = 0.376，科恩d值 = 0.22），随后在HIIT后有更大幅度的增加（16.9±4.4μg·dl），与基线相比显著升高（p = 0.002，科恩d值 = 0.85），与预处理后相比也显著升高（p = 0.005，科恩d值 = 0.51）。LEX组从A阶段到B阶段IGF-I有微小变化（18.2±6.4降至17.2±3.7μg·dl [p = 0.538，科恩d值 = 0.19]），HIIT后有小幅变化（18.4±4.1μg·dl [p = 0.283，科恩d值 = 0.31]）。两组在HIIT后无脂肪体重均有小幅增加（p < 0.05，科恩d值 = 0.32 - 0.45）。
总之，进行预处理运动的HIIT消除了SED组和LEX组之间与年龄相关的IGF-I差异，并使SED组和LEX组的无脂肪体重都有小幅改善。
