Borisova E V, Sabo G, Zhuravlev B V, Telegdi G
Biull Eksp Biol Med. 1989 Aug;108(8):132-5.
The administration of neuropeptide Y in lower doses (1 and 100 ng/rat) into the lateral ventricle of the brain gave rise to the inhibition of locomotor activity, weakening of the orienting-exploratory behaviour, increase in the period of rest in animals. Feeding and drinking behaviour after the administration of neuropeptide was not observed. Alterations of behaviour in rats were followed by a dose-depended increase in noradrenaline in hypothalamus. No changes were observed in the content of noradrenaline in the frontal cortex and septum. Some variations in the level of noradrenaline were found in amygdala and hippocamp. It may be assumed that behavioural effects, aroused by the central administration of neuropeptide Y, is connected with the activation of catecholaminergic systems of hypothalamus.
向大鼠脑侧脑室注射低剂量（1和100纳克/大鼠）的神经肽Y会导致运动活动受到抑制、定向探索行为减弱、动物休息时间增加。注射神经肽后未观察到进食和饮水行为。大鼠行为的改变伴随着下丘脑去甲肾上腺素剂量依赖性增加。额叶皮质和隔区的去甲肾上腺素含量未观察到变化。杏仁核和海马体中去甲肾上腺素水平有一些变化。可以推测，中枢注射神经肽Y引起的行为效应与下丘脑儿茶酚胺能系统的激活有关。
