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[高频人工通气中气体交换的强化]

[Intensification of gas exchange in high-frequency artificial ventilation].

作者信息

Nemerovskiĭ L I, Vikhrov E V, Levité E M, Raĭnov M M

出版信息

Biull Eksp Biol Med. 1989 Aug;108(8):142-4.

PMID:2804314
Abstract

Jet high-frequency artificial ventilation produces oscillations of some parts of the chest wall, which in its turn transmits oscillations to the lung parenchyma. It results in the mix-up of the gas in the alveolar space, which leads to the increase in the gradient of oxygen concentration on the alveolar membranes, thus, augmenting oxygen saturation of the blood. The effect is the same when oscillation artificial ventilation is performed, owing to the provocation of the oscillations amplified by the resonance in the natural acoustic circuit, formed by the adjacent parts of the chest and lung parenchyma. Derangement of the exudative adhesion to the bronchi epithelial tissue intensifies gas exchange, when the oscillations are generated in the lungs. It facilitates the removal of the exudate and lets the air into the previously obstructed parts of the lungs. Clinical studies confirm the effect of the increase in the blood oxygenation (by average 20%) at the feeding air column by pneumatic oscillations in the range of 65 Hz, when traditional artificial ventilation is performed.

摘要

喷射高频人工通气会使胸壁的某些部位产生振荡,进而将振荡传递至肺实质。这会导致肺泡腔内气体混合,从而使肺泡膜上的氧浓度梯度增加,进而提高血液的氧饱和度。当进行振荡人工通气时,由于胸部和肺实质相邻部分形成的自然声学回路中的共振放大了振荡,效果是相同的。当肺部产生振荡时,支气管上皮组织渗出性粘连的紊乱会加强气体交换。这有助于清除渗出物,并使空气进入先前阻塞的肺部区域。临床研究证实,在进行传统人工通气时,当以65赫兹的气动振荡输送气柱时,血液氧合作用会增强(平均增加20%)。

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