Harkey M S, Blackburn J T, Davis H, Sierra-Arévalo L, Nissman D, Pietrosimone B
Department of Exercise and Sports Science, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States; Human Movement Science Curriculum, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.
Department of Exercise and Sports Science, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.
Osteoarthritis Cartilage. 2017 Jun;25(6):907-913. doi: 10.1016/j.joca.2016.12.026. Epub 2016 Dec 31.
To determine the magnitude of medial femoral cartilage deformation using ultrasonography (US) following walking and running in healthy individuals.
Twenty-five healthy participants with no history of osteoarthritis or knee injury volunteered for this study. Medial femoral cartilage thickness was assessed using US before and after three separate 30-min loading conditions: (1) walking at a self-selected speed, (2) running at a self-selected speed, and (3) sitting on a treatment table (i.e., control). Cartilage deformation was calculated as the percent change score from pre to post loading in each loading condition. The magnitude of cartilage deformation was compared between the three loading conditions.
There was no difference in baseline cartilage thickness between the three sessions (F = 0.18, P = 0.68). Cartilage deformation was different between the loading conditions (F = 47.54, P < 0.001). The walking (%Δ = -6.7, t = 6.90, P < 0.001, d = -1.92) and running (%Δ = -8.9, t = 8.14, P < 0.001, d = -1.85) conditions resulted in greater cartilage deformation when compared to the control condition (%Δ = +3.4). There was no difference in cartilage deformation between the running and walking conditions (t = 1.10, P = 0.28, d = 0.33). US measured medial femoral cartilage thickness demonstrated reliability and precision within a single session (ICC = 0.966, SEM = 0.07 mm) and between additional sessions separated by seven (ICC = 0.964, SEM = 0.08 mm) and 16 days (ICC = 0.919, SEM = 0.11 mm).
US demonstrated to be a reliable and sensitive imaging modality at quantifying medial femoral cartilage deformation in healthy individuals. Both walking and running conditions created greater cartilage deformation when compared to the control conditions, but no difference was observed between the walking and running conditions.
使用超声（US）测定健康个体在行走和跑步后股骨内侧软骨变形的程度。
25名无骨关节炎或膝关节损伤病史的健康参与者自愿参加本研究。在三种不同的30分钟负荷条件前后，使用超声评估股骨内侧软骨厚度：（1）以自选速度行走，（2）以自选速度跑步，（3）坐在治疗台上（即对照）。软骨变形计算为每种负荷条件下负荷前至负荷后的变化百分比得分。比较三种负荷条件下软骨变形的程度。
三次测量的基线软骨厚度无差异（F = 0.18，P = 0.68）。负荷条件之间的软骨变形不同（F = 47.54，P < 0.001）。与对照条件（变化百分比= +3.4）相比，行走（变化百分比= -6.7，t = 6.90，P < 0.001，d = -1.92）和跑步（变化百分比= -8.9，t = 8.14，P < 0.001，d = -1.85）条件导致更大的软骨变形。跑步和行走条件之间的软骨变形无差异（t = 1.10，P = 0.28，d = 0.33）。超声测量的股骨内侧软骨厚度在单次测量中（组内相关系数ICC = 0.966，标准误SEM = 0.07毫米）以及相隔7天（ICC = 0.964，SEM = 0.08毫米）和16天（ICC = 0.919，SEM = 0.11毫米）的额外测量之间显示出可靠性和精确性。
超声被证明是一种可靠且敏感的成像方式，可用于量化健康个体的股骨内侧软骨变形。与对照条件相比，行走和跑步条件均导致更大的软骨变形，但行走和跑步条件之间未观察到差异。
