通过氨基自由基-极性交叉策略实现叠氮化物与醛腙的[3+2]环加成反应。
[3+2] Cycloaddition of azide with aldehyde hydrazone through an aminyl radical-polar crossover strategy.
作者信息
Wu Zhongkai, Xu Pan, Zhou Nengneng, Duan Yingqian, Zhang Muliang, Zhu Chengjian
机构信息
State Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, P. R. China.
出版信息
Chem Commun (Camb). 2017 Jan 17;53(6):1045-1047. doi: 10.1039/c6cc08779e.
PMID:28044151
Abstract
A novel approach to obtain functionalized tetrazoles by a [3+2] cycloaddition of azide with aldehyde hydrazone is reported. This reaction features a broad substrate scope and mild reaction conditions through an aminyl radical-polar crossover strategy.
摘要
报道了一种通过叠氮化物与醛腙的[3+2]环加成反应获得功能化四唑的新方法。该反应通过氨基自由基-极性交叉策略，具有广泛的底物范围和温和的反应条件。
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