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美国腰椎间盘突出症患者的非手术治疗选择:与长期预后的关联

Nonsurgical Treatment Choices by Individuals with Lumbar Intervertebral Disc Herniation in the United States: Associations with Long-term Outcomes.

作者信息

Thackeray Anne, Fritz Julie M, Lurie Jon D, Zhao Wenyan, Weinstein James N

机构信息

From the Department of Physical Therapy, University of Utah, Salt Lake City (AT, JMF); Intermountain Health Care, Salt Lake City, Utah (JMF); Department of Medicine, Dartmouth Medical School, Hanover, New Hampshire (JDL, JNW); The Dartmouth Institute for Health Policy and Clinical Practice, Dartmouth College, Hanover, New Hampshire (JDL, WZ, JNW); Department of Orthopaedics, Dartmouth Medical School, Hanover, New Hampshire (WZ, JNW); and Dartmouth-Hitchcock, Lebanon, New Hampshire (JNW).

出版信息

Am J Phys Med Rehabil. 2017 Aug;96(8):557-564. doi: 10.1097/PHM.0000000000000685.

Abstract

OBJECTIVES

The objectives of this study were to (1) evaluate differences between patients with lumbar intervertebral disc herniation who received physical therapy (PT) and those who did not; (2) identify factors associated with receiving PT; and (3) examine the influence of PT on clinical outcomes over the course of 1 yr.

DESIGN

An observational cohort study using data from the Spine Patient Outcomes Research Trial was conducted. This study included 363 patients with intervertebral disc herniation who received nonsurgical management within 6 wks of enrollment. Baseline characteristics were compared between patients who received PT and those who did not. Multivariate logistic regression examined factors predictive of patients receiving PT. Mixed effects models were used to compare primary outcomes (Short-Form Survey 36 bodily pain and physical function and modified Oswestry Index) at 3 and 6 mos and 1 yr after enrollment.

RESULTS

Forty percent of the nonsurgical cohort received PT. Higher disability scores, neurological deficit, and patient preference predicted PT use. Compared with other nonsurgical management strategies, standard care PT was not associated with a significant difference in pain, disability, or surgery over 1 yr.

CONCLUSIONS

Many patients with intervertebral disc herniation seek secondary care for persisting symptoms and pursue nonsurgical management. The best management strategy is unclear and further research is needed to examine appropriate sequencing and selection of treatment.

摘要

目的

本研究的目的是:(1)评估接受物理治疗(PT)的腰椎间盘突出症患者与未接受物理治疗的患者之间的差异;(2)确定与接受物理治疗相关的因素;(3)在1年的时间里检查物理治疗对临床结果的影响。

设计

使用来自脊柱患者结果研究试验的数据进行了一项观察性队列研究。本研究纳入了363例椎间盘突出症患者,这些患者在入组后6周内接受了非手术治疗。比较了接受物理治疗和未接受物理治疗的患者的基线特征。多变量逻辑回归分析了预测患者接受物理治疗的因素。使用混合效应模型比较入组后3个月、6个月和1年时的主要结局(简短36项健康调查躯体疼痛和身体功能以及改良Oswestry指数)。

结果

非手术队列中有40%的患者接受了物理治疗。较高的残疾评分、神经功能缺损和患者偏好可预测物理治疗的使用情况。与其他非手术治疗策略相比,标准护理物理治疗在1年期间的疼痛、残疾或手术方面没有显著差异。

结论

许多腰椎间盘突出症患者因持续症状寻求二级护理并采用非手术治疗。最佳治疗策略尚不清楚,需要进一步研究以检查治疗的适当顺序和选择。

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