1 Stroke Unit - Department of Emergency Medicine, AO S Camillo Forlanini, Rome, Italy.
2 Direzione Scientifica and U.O. Medicina d'Urgenza, Fondazione IRCCS Cà Granda, Ospedale Maggiore Policlinico, Milan, Italy.
Int J Stroke. 2014 Oct;9(SA100):20-27. doi: 10.1111/ijs.12110.
We describe the current and future objectives of the Women Stroke Association, a nonprofit multidisciplinary organization promoting research awareness on medical, psychological, and social issues concerning women affected by cerebrocardiovascular disease. In this paper, we deal with only cerebrovascular disease, whereas cardiovascular disorders will be addressed in a future paper. Gender differences in the clinical presentation of cerebrovascular diseases have been repeatedly suggested, and some treatment options may not be as effective and safe in men and women. For many years, women have either been underrepresented or excluded from randomized clinical trials, and the majority of therapeutic research has been carried on predominantly male populations. Furthermore, gender differences have been shown to contribute to different responses to cerebrovascular drugs in women when compared with men, regarding pharmacokinetics, pharmacodynamics, and physiology. In this statement, we discuss main research fields relevant to Women Stroke Association's mission and commitment, highlighting opportunities and critical from the women's health perspective. Future directions and goals of the Women Stroke Association arise from these considerations and represent the association's commitment to combating stroke.
我们介绍了妇女卒中协会（Women Stroke Association）的当前和未来目标，该协会是一个非营利性多学科组织，旨在提高对涉及受脑血管疾病影响的妇女的医学、心理和社会问题的研究意识。在本文中，我们仅涉及脑血管疾病，而心血管疾病将在以后的论文中讨论。脑血管疾病的临床表现存在性别差异，一些治疗选择在男性和女性中的效果和安全性可能不同。多年来，女性在随机临床试验中要么代表性不足，要么被排除在外，大多数治疗研究主要针对男性人群进行。此外，与男性相比，女性的药代动力学、药效学和生理学方面的差异表明，女性对脑血管药物的反应也不同。在本声明中，我们讨论了与妇女卒中协会的使命和承诺相关的主要研究领域，突出了从妇女健康角度来看的机会和关键问题。妇女卒中协会的未来方向和目标源于这些考虑，代表了该协会对抗卒中的承诺。
