Łoś-Rycharska Ewa, Kieraszewicz Zuzanna, Czerwionka-Szaflarska Mieczysława
Department and Clinic of Paediatrics, Allergology, and Gastroenterology, Nicolaus Copernicus University in Torun, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Poland.
Prz Gastroenterol. 2016;11(4):226-231. doi: 10.5114/pg.2016.61374. Epub 2016 Jul 20.
Fats constitute the most significant nutritional source of energy. Their proper use by the body conditions a number of complex mechanisms of digestion, absorption, distribution, and metabolism. These mechanisms are facilitated by fats made of medium chain fatty acids; therefore, they are an easy and quick source of energy. Thus, an increased supply of medium chain triglycerides (MCT) is particularly important in patients with disturbances of digestion and absorption such as disturbed bile secretion, classic coeliac disease, short bowel syndrome, inflammatory diseases of the intestines, disturbed outflow of lymph, some metabolic disease, and severe food allergies, as well as in prematurely born neonates. Use of preparations containing an additive of MCT is limited, especially if they are to be used for a longer period of time. With a large quantity of MCT in a diet, there is a risk of deficiency of necessary unsaturated fatty acids and some fat-soluble vitamins. The caloricity of MTC compared to long-chain triglycerides is lower, and formulas with MCT are characterised by higher osmolality. Medium chain triglycerides is not recommended as an additive to standard formulas for healthy children. The use of MCT should be limited to strictly specified medical indications.
脂肪是最重要的营养能量来源。身体对其的合理利用取决于许多复杂的消化、吸收、分布和代谢机制。由中链脂肪酸构成的脂肪有助于这些机制,因此,它们是一种简便快捷的能量来源。因此,对于患有消化和吸收障碍的患者,如胆汁分泌紊乱、典型乳糜泻、短肠综合征、肠道炎症性疾病、淋巴引流不畅、某些代谢疾病和严重食物过敏的患者,以及早产新生儿,增加中链甘油三酯(MCT)的供应尤为重要。含有MCT添加剂的制剂使用受限,尤其是如果要长期使用的话。饮食中含有大量MCT时,存在必需不饱和脂肪酸和一些脂溶性维生素缺乏的风险。与长链甘油三酯相比,MTC的热量较低,含MCT的配方奶粉具有较高的渗透压。不建议将中链甘油三酯作为健康儿童标准配方奶粉的添加剂。MCT的使用应限于严格规定的医学适应症。