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伴有无症状脊髓受累的可逆性后部白质脑病综合征(PRES)。这种情况是否比我们所知的更常见?

PRES with asymptomatic spinal cord involvement. Is this scenario more common than we know?

作者信息

Marrone L C P, Martins W A, Brunelli J P F, Fussiger H, Carvalhal G F, Filho J R H, Soder R B, Schuck M, Viola F S, Marrone A C H, da Costa J C

机构信息

Hospital São Lucas/Instituto do Cérebro-Pontificia Universidade Católicas do Rio Grande do Sul (PUCRS) , Porto Alegre, Brazil.

出版信息

Spinal Cord Ser Cases. 2016 Jan 7;2:15001. doi: 10.1038/scsandc.2015.1. eCollection 2016.

Abstract

INTRODUCTION

Posterior reversible encephalopathy syndrome (PRES) is an entity characterized by neurologic symptoms such as headaches, altered mental status, seizures and visual changes, and it is associated with white matter vasogenic edema predominantly affecting the posterior occipital and parietal lobes of the brain.

CASE REPORT

A 19-year-old patient developed PRES after the use of chemotherapy for a testicular teratocarcinoma and after the development of a blood pressure elevation.

DISCUSSION

Few cases described the involvement of the spinal cord in this syndrome. In the majority of these cases, the spinal cord involvement was asymptomatic or with few symptoms of spinal cord disease.

摘要

引言

后部可逆性脑病综合征(PRES)是一种以头痛、精神状态改变、癫痫发作和视觉变化等神经症状为特征的病症,它与主要影响大脑枕叶和顶叶的白质血管源性水肿相关。

病例报告

一名19岁患者在接受睾丸畸胎癌化疗后且血压升高后患上了PRES。

讨论

很少有病例描述该综合征累及脊髓。在大多数此类病例中,脊髓受累无症状或仅有很少的脊髓疾病症状。

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本文引用的文献

1
Posterior reversible encephalopathy syndrome with spinal cord involvement.伴有脊髓受累的后部可逆性脑病综合征
Neurology. 2014 Nov 25;83(22):2002-6. doi: 10.1212/WNL.0000000000001026. Epub 2014 Oct 29.
2
Posterior reversible encephalopathy syndrome following a scorpion sting.蝎蜇伤后可逆性后部脑病综合征。
J Neuroimaging. 2013 Oct;23(4):535-6. doi: 10.1111/jon.12017. Epub 2013 Apr 3.
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[Posterior reversible encephalopathy syndrome (pres) in sepsis].[脓毒症中的后部可逆性脑病综合征(PRES)]
Med Intensiva. 2012 Dec;36(9):656-8. doi: 10.1016/j.medin.2012.03.005. Epub 2012 Apr 27.
10
Asymptomatic spinal cord involvement in posterior reversible encephalopathy syndrome.
Neurology. 2010 May 4;74(18):1478-9; author reply 1479. doi: 10.1212/WNL.0b013e3181d8a4a3.

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