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伴有广泛性索分化、异源性成分及复杂性非典型增生的低级别子宫内膜间质肉瘤:病例报告及文献复习

Low-grade endometrial stromal sarcoma with extensive sex cord differentiation, heterologous elements, and complex atypical hyperplasia: Case report and review of literature.

作者信息

Richmond Abby M, Rohrer Andrew J, Davidson Susan A, Post Miriam D

机构信息

University of Colorado, Department of Pathology, Aurora, CO, United States.

Denver Health Medical Center, Department of Obstetrics and Gynecology, Denver, CO, United States.

出版信息

Gynecol Oncol Rep. 2016 Dec 14;19:34-38. doi: 10.1016/j.gore.2016.12.002. eCollection 2017 Feb.

Abstract

•Endometrial stromal sarcoma (ESS) may have sex cord differentiation, usually focal.•Diagnosis of ESS is difficult when variant morphology predominates.•Prognosis differs between ESS and UTROSCT; therefore, distinction is critical.•Extensive tumor sampling is mandatory to identify neoplastic endometrial stroma.•Sex cord differentiation may be associated with endometrial hyperplasia.

摘要

•子宫内膜间质肉瘤(ESS)可能具有性索分化,通常为局灶性。

•当变异形态占主导时,ESS的诊断较为困难。

•ESS和子宫未分化肉瘤(UTROSCT)的预后不同;因此,鉴别至关重要。

•必须进行广泛的肿瘤取材以识别肿瘤性子宫内膜间质。

•性索分化可能与子宫内膜增生有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd26/5199152/c1513d93324e/gr1.jpg

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Endometrial stromal sarcoma--the new genetic paradigm.子宫内膜间质肉瘤——新的遗传模式。
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Endometrial stromal tumors: the new WHO classification.子宫内膜间质肿瘤:世界卫生组织新分类
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