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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Iwase N, Takata S, Ogawa J, Oukuwa H, Ikeda T, Hattori N

First Department of Internal Medicine, Kanazawa University, Japan.

Clin Exp Pharmacol Physiol Suppl. 1989;15:109-11. doi: 10.1111/j.1440-1681.1989.tb03004.x.

The effects of sodium loading on cardiopulmonary baroreflex control of forearm vasoconstriction were studied using lower body negative pressure (LBNP) in 12 healthy young subjects. 2. Before and during sodium loading, there was no significant change in mean blood pressure, heart rate, central venous pressure (CVP) or forearm vascular resistance (FVR). 3. The degree of reflex increase in FVR during LBNP at -10, -20, and -40 mmHg was significantly greater during sodium loading than regular diet. 4. During sodium loading, the slope of the regression line relating percent change in FVR and change in CVP was significantly increased. 5. These results suggest that sodium loading augments cardiopulmonary baroreflex sensitivity of FVR in normotensive subjects without a family history of hypertension.

采用下体负压（LBNP）对12名健康年轻受试者进行研究，以探讨钠负荷对心肺压力反射控制前臂血管收缩的影响。2. 在钠负荷前后，平均血压、心率、中心静脉压（CVP）或前臂血管阻力（FVR）均无显著变化。3. 在-10、-20和-40 mmHg的下体负压期间，钠负荷时FVR反射性增加的程度显著大于正常饮食时。4. 在钠负荷期间，FVR百分比变化与CVP变化之间的回归线斜率显著增加。5. 这些结果表明，钠负荷可增强无高血压家族史的正常血压受试者中FVR的心肺压力反射敏感性。

Iwase N, Takata S, Ogawa J, Oukuwa H, Ikeda T, Hattori N

First Department of Internal Medicine, Kanazawa University, Japan.

Clin Exp Pharmacol Physiol Suppl. 1989;15:109-11. doi: 10.1111/j.1440-1681.1989.tb03004.x.

The effects of sodium loading on cardiopulmonary baroreflex control of forearm vasoconstriction were studied using lower body negative pressure (LBNP) in 12 healthy young subjects. 2. Before and during sodium loading, there was no significant change in mean blood pressure, heart rate, central venous pressure (CVP) or forearm vascular resistance (FVR). 3. The degree of reflex increase in FVR during LBNP at -10, -20, and -40 mmHg was significantly greater during sodium loading than regular diet. 4. During sodium loading, the slope of the regression line relating percent change in FVR and change in CVP was significantly increased. 5. These results suggest that sodium loading augments cardiopulmonary baroreflex sensitivity of FVR in normotensive subjects without a family history of hypertension.

采用下体负压（LBNP）对12名健康年轻受试者进行研究，以探讨钠负荷对心肺压力反射控制前臂血管收缩的影响。2. 在钠负荷前后，平均血压、心率、中心静脉压（CVP）或前臂血管阻力（FVR）均无显著变化。3. 在-10、-20和-40 mmHg的下体负压期间，钠负荷时FVR反射性增加的程度显著大于正常饮食时。4. 在钠负荷期间，FVR百分比变化与CVP变化之间的回归线斜率显著增加。5. 这些结果表明，钠负荷可增强无高血压家族史的正常血压受试者中FVR的心肺压力反射敏感性。