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磁场远程控制 DNA 水凝胶。

Remote Controlling DNA Hydrogel by Magnetic Field.

机构信息

School of Basic Medical Sciences, Lanzhou University , Lanzhou, Gansu 730000, China.

Key Laboratory of Organic Optoelectronics and Molecular Engineering of the Ministry of Education, Department of Chemistry, Tsinghua University , Beijing 100084, China.

出版信息

ACS Appl Mater Interfaces. 2017 Jan 25;9(3):1995-2000. doi: 10.1021/acsami.6b12327. Epub 2017 Jan 11.

Abstract

DNA hydrogel has aroused widespread attention because of its unique properties. In this work, the DNA-modified magnetic nanoparticles were integrated into the mainframe of DNA hydrogel, resulting in DNA-MNP hydrogel. Under the magnetic field, this hydrogel can be remotely deformed into various shapes, driven to jump between two planes and even climb the hill. By applying various triggers, such as temperature, enzyme, and magnetic field, DNA-MNP hydrogel can specifically undergo sol-gel transition. This work not only imparts DNA hydrogel with a new fold of property but also opens a unique platform of such smart materials for its further applications.

摘要

DNA 水凝胶因其独特的性质而引起了广泛的关注。在这项工作中,将经过 DNA 修饰的磁性纳米颗粒整合到 DNA 水凝胶的主体结构中,得到 DNA-MNP 水凝胶。在磁场的作用下,这种水凝胶可以远程变形为各种形状,被驱动在两个平面之间跳跃,甚至可以爬坡。通过施加各种触发条件,如温度、酶和磁场,DNA-MNP 水凝胶可以特异性地发生溶胶-凝胶转变。这项工作不仅为 DNA 水凝胶赋予了一种新的性质,还为这类智能材料的进一步应用开辟了一个独特的平台。

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