卵巢癌中的副肿瘤性自身免疫性溶血性贫血：疾病活动的标志物。
Paraneoplastic autoimmune hemolytic anemia in ovarian cancer: a marker of disease activity.
作者信息
Loh Kah Poh, Kansagra Ankit, Asik Armen, Ali Syed, Dahiya Saurabh
机构信息
Division of General Medicine, Baystate Medical Center/Tufts University School of Medicine , Springfield, MA, USA.
Division of Hematology/Oncology, Department of Medicine, Baystate Medical Center/Tufts University School of Medicine , Springfield, MA, USA.
出版信息
Rare Tumors. 2015 Feb 11;7(1):5598. doi: 10.4081/rt.2015.5598.
Autoimmune hemolytic anemia (AIHA) is a rare paraneoplastic syndrome associated with ovarian malignancies. We report a case of a 77 year-old female with metastatic ovarian carcinoma who presented with worsening anemia from her baseline, and was found to have a warm autoimmune hemolytic anemia. We performed a literature review and analyzed all 10 cases (including our patient) that have been reported to date, and incorporated the clinical presentation, histology and stage of underlying malignancies, types, treatment, prognosis and mechanisms of AIHA in ovarian carcinoma.
自身免疫性溶血性贫血（AIHA）是一种与卵巢恶性肿瘤相关的罕见副肿瘤综合征。我们报告一例77岁转移性卵巢癌女性患者，其贫血症状较基线水平加重，被诊断为温抗体型自身免疫性溶血性贫血。我们进行了文献综述，分析了迄今为止报道的所有10例病例（包括我们的患者），并纳入了卵巢癌中AIHA的临床表现、潜在恶性肿瘤的组织学和分期、类型、治疗、预后及机制。
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