Li Peng, Jin Jun, Wang Ying, Hu Jicheng, Xu Meng, Sun Yiming, Ma Yulong
College of Life and Environment Sciences, Minzu University of China, Beijing 100081, China.
College of Life and Environment Sciences, Minzu University of China, Beijing 100081, China; Engineering Research Center of Food Environment and Public Health, Beijing 100081, China.
Chemosphere. 2017 Mar;171:654-660. doi: 10.1016/j.chemosphere.2016.12.126. Epub 2016 Dec 27.
Organophosphorus flame retardants, polybromobenzenes, and polybrominated diphenyl ethers (PBDEs) were determined in pooled human serum samples collected in an area in which these chemicals are produced in North China. Tri (2-chloroethyl) phosphate (TCEP) was found at a higher concentration than the other chemicals, and the mean TCEP concentration was 480.4 ng/g lipid. This is the first time TCEP has been detected in human serum from China. The PBDE concentration in serum was found to have decreased between 2007 and 2013. BDE-209 remained the dominant PBDE congener, and its mean concentration was 91.3 ng/g lipid in this study. The polybromobenzene concentrations were relatively low, but pentabromobenzene and pentabromotoluene were found in very many of the samples. The highest TCEP, tris(2-butoxyethyl)phosphate, pentabromobenzene, and pentabromotoluene concentrations were found in samples from young people (<30 y old). This suggests that the risks posed by these alternative flame retardants also need more concerns.
在中国北方某化学物质生产地区采集的人体血清混合样本中，对有机磷阻燃剂、多溴苯和多溴二苯醚（PBDEs）进行了测定。发现磷酸三（2-氯乙基）酯（TCEP）的浓度高于其他化学物质，其平均浓度为480.4纳克/克脂质。这是首次在中国人体血清中检测到TCEP。血清中多溴二苯醚的浓度在2007年至2013年间有所下降。在本研究中，BDE-209仍然是主要的多溴二苯醚同系物，其平均浓度为91.3纳克/克脂质。多溴苯的浓度相对较低，但在许多样本中都发现了五溴苯和五溴甲苯。在年轻人（<30岁）的样本中，TCEP、磷酸三（2-丁氧基乙基）酯、五溴苯和五溴甲苯的浓度最高。这表明这些替代阻燃剂带来的风险也需要更多关注。
