Grossman Alon, Grossman Ehud
Department of Internal Medicine E, Rabin Medical Center, Petach Tikva, Israel.
Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
Cardiovasc Diabetol. 2017 Jan 6;16(1):3. doi: 10.1186/s12933-016-0485-3.
Diabetes mellitus (DM) and essential hypertension are common conditions that are frequently present together. Both are considered risk factors for cardiovascular disease and microvascular complications and therefore treatment of both conditions is essential. Many papers were published on blood pressure (BP) targets in diabetic patients, including several works published in the last 2 years. As a result, guidelines differ in their recommendations on BP targets in diabetic patients. The method by which to control hypertension, whether pharmacological or non-pharmacological, is also a matter of debate and has been extensively studied in the literature. In recent years, new medications were introduced for the treatment of DM, some of which also affect BP and the clinician treating hypertensive and diabetic patients should be familiar with these medications and their effect on BP. In this manuscript, we discuss the evidence supporting different BP targets in diabetics and review the various guidelines on this topic. In addition, we discuss the various options available for the treatment of hypertension in diabetics and the recommendations for a specific treatment over the other. Finally we briefly discuss the new diabetic drug classes and their influence on BP.
糖尿病（DM）和原发性高血压是常见病症，常同时出现。两者均被视为心血管疾病和微血管并发症的危险因素，因此对这两种病症的治疗至关重要。关于糖尿病患者血压（BP）目标的论文发表了很多，包括过去两年发表的几篇研究。结果，不同指南对糖尿病患者血压目标的建议存在差异。控制高血压的方法，无论是药物治疗还是非药物治疗，也是一个有争议的问题，并且在文献中已得到广泛研究。近年来，用于治疗糖尿病的新药问世，其中一些药物也会影响血压，治疗高血压和糖尿病患者的临床医生应熟悉这些药物及其对血压的影响。在本手稿中，我们讨论支持糖尿病患者不同血压目标的证据，并回顾关于该主题的各种指南。此外，我们讨论糖尿病患者高血压治疗的各种可用选择以及针对特定治疗优于其他治疗的建议。最后，我们简要讨论新型糖尿病药物类别及其对血压的影响。
