Aljohi Alanood Ahmed, Hassan Hanan Elkefafy, Gupta Rakesh Kumar
Department of Internal Medicine, Intensive Care Unit, King Fahad University Hospital, University of Dammam, Al Khobar, Saudi Arabia.
Urol Ann. 2016 Oct-Dec;8(4):423-429. doi: 10.4103/0974-7796.192099.
Catheter-associated urinary tract infection (CAUTI) is the most common device-related healthcare-acquired infection. CAUTI can be severe and lead to bacteremia, significant morbidity, prolonged hospital stay, and high antibiotic consumption.
In this study, we evaluated the CAUTI-reducing efficacy of noble metal alloy catheters in sixty patients (thirty per group) in the Intensive Care Unit (ICU) at the King Fahad Hospital in Saudi Arabia. The study was a single-blinded, randomized, single-centered, prospective investigation that included patients using urinary catheters for 3 days.
A 90% relative risk reduction in the rate of CAUTI was observed with the noble metal alloy catheter compared to the standard catheter (10 vs. 1 cases, = 0.006). When considering both catheter-associated asymptomatic bacteriuria and CAUTI, the relative risk reduction was 83% (12 vs. 2 cases, = 0.005). In addition to CAUTI, the risk of acquiring secondary bacteremia was lower (100%) for the patients using noble metal alloy catheters (3 cases in the standard group vs. 0 case in the noble metal alloy catheter group, = 0.24). No adverse events related to any of the used catheters were recorded.
Results from this study revealed that noble metal alloy catheters are safe to use and significantly reduce CAUTI rate in ICU patients after 3 days of use.
导尿管相关尿路感染（CAUTI）是最常见的与器械相关的医疗保健获得性感染。CAUTI可能很严重，并导致菌血症、显著的发病率、延长住院时间以及大量使用抗生素。
在本研究中，我们评估了贵金属合金导尿管在沙特阿拉伯法赫德国王医院重症监护病房（ICU）的60例患者（每组30例）中降低CAUTI的效果。该研究是一项单盲、随机、单中心的前瞻性调查，纳入使用导尿管3天的患者。
与标准导尿管相比，使用贵金属合金导尿管时CAUTI发生率相对风险降低了90%（10例对1例，P = 0.006）。当同时考虑导尿管相关无症状菌尿症和CAUTI时，相对风险降低了83%（12例对2例，P = 0.005）。除CAUTI外，使用贵金属合金导尿管的患者发生继发性菌血症的风险也较低（100%）（标准组3例，贵金属合金导尿管组0例，P = 0.24）。未记录到与任何使用的导尿管相关的不良事件。
本研究结果表明，贵金属合金导尿管使用安全，在ICU患者使用3天后可显著降低CAUTI发生率。
