Suppr超能文献

复发性扁桃体咽炎患儿的血清维生素D水平

Serum vitamin D levels in children with recurrent tonsillopharyngitis.

作者信息

Collak Abdulhamit, Bozaykut Abdulkadir, Demirel Bilge, Sezer Rabia Gonul, Seren Lale Pulat, Dogru Mahmut

机构信息

Department of Pediatrics, Zeynep Kamil Maternity and Children's Diseases Training and Research Hospital, Istanbul, Turkey.

Department of Pediatric Allergy and Immunology, Zeynep Kamil Maternity and Children's Diseases Training and Research Hospital, Istanbul, Turkey.

出版信息

North Clin Istanb. 2014 Aug 3;1(1):13-18. doi: 10.14744/nci.2014.76486. eCollection 2014.

Abstract

OBJECTIVE

In this study, we aimed to compare vitamin D levels of children with recurrent tonsillopharingitis and healthy controls, and investigate the relationship between sociodemographic characteristics and serum vitamin D levels.

METHODS

Children with recurrent tonsillopharingitis and healthy controls aged between 2, and 12 years who consulted to the outpatient clinics of Zeynep Kamil Maternity and Children's Diseases Training and Research Hospital from January to October 2012 were included in this study. Serum 25 (OH) vitamin D levels were studied by tandem mass spectroscopy (tandem ms) method. Risk factors which might be associated with vitamin D levels were questioned. Ethical aproval was obtained from the Ethics Committee of Zeynep Kamil Maternity and Children's Diseases Training and Research Hospital and informed consent from the parents of the children.

RESULTS

A total of 147 children; 74 (50.3%) patients and 73 (49.7%) controls were included in our study. Age, gender and demographic characteristics did not differ significantly between the two groups. Vitamin D levels in patients with recurrent tonsillopharingitis and controls were 19.7±8.7 ng/ml and 23.6±9.2 ng/ml, respectively (p<0.01). Although duration of vitamin D usage was shorter in children with recurrent tonsillopharingitis, this difference was not statistically significant (p>0.05).

CONCLUSION

Vitamin D levels in children with ≥7 recurrent episodes of tonsillophargitis within the preceeding year were significantly lower compared to the control group. We believe that serum vitamin D levels should be checked in children with recurrent tonsillopharingitis and deficiencies should be treated.

摘要

目的

在本研究中,我们旨在比较复发性扁桃体咽炎患儿与健康对照者的维生素D水平,并调查社会人口学特征与血清维生素D水平之间的关系。

方法

纳入2012年1月至10月在泽伊内普·卡米尔妇产儿童医院门诊就诊的2至12岁复发性扁桃体咽炎患儿及健康对照者。采用串联质谱法研究血清25(OH)维生素D水平。对可能与维生素D水平相关的危险因素进行了询问。获得了泽伊内普·卡米尔妇产儿童医院伦理委员会的伦理批准,并获得了患儿家长的知情同意。

结果

本研究共纳入147名儿童;74名(50.3%)患者和73名(49.7%)对照者。两组在年龄、性别和人口学特征方面无显著差异。复发性扁桃体咽炎患者和对照者的维生素D水平分别为19.7±8.7 ng/ml和23.6±9.2 ng/ml(p<0.01)。虽然复发性扁桃体咽炎患儿使用维生素D的时间较短,但这种差异无统计学意义(p>0.05)。

结论

与对照组相比,前一年扁桃体咽炎发作≥7次的患儿维生素D水平显著降低。我们认为,对于复发性扁桃体咽炎患儿应检查血清维生素D水平,如有缺乏应进行治疗。

相似文献

1
Serum vitamin D levels in children with recurrent tonsillopharyngitis.
North Clin Istanb. 2014 Aug 3;1(1):13-18. doi: 10.14744/nci.2014.76486. eCollection 2014.
2
The association between vitamin D levels and recurrent group A streptococcal tonsillopharyngitis in adults.
Int J Infect Dis. 2012 Oct;16(10):e735-8. doi: 10.1016/j.ijid.2012.05.1036. Epub 2012 Jul 26.
3
Serum Vitamin D Levels in Children with Recurrent Respiratory Infections and Chronic Cough.
Indian J Pediatr. 2016 Aug;83(8):777-82. doi: 10.1007/s12098-015-2010-1. Epub 2016 Jan 29.
5
[Vitamin D status in children with cow's milk allergy].
Med Wieku Rozwoj. 2012 Oct-Dec;16(4):307-12.
8
The relation between serum vitamin D levels, viral infections and severity of attacks in children with recurrent wheezing.
Allergol Immunopathol (Madr). 2019 Nov-Dec;47(6):591-597. doi: 10.1016/j.aller.2019.05.002. Epub 2019 Aug 30.
10
Serum Vitamin D Status and Outcome among Critically Ill Children Admitted to the Pediatric Intensive Care Unit in South India.
Indian J Pediatr. 2016 Feb;83(2):120-5. doi: 10.1007/s12098-015-1833-0. Epub 2015 Jul 19.

引用本文的文献

本文引用的文献

1
The association between vitamin D levels and recurrent group A streptococcal tonsillopharyngitis in adults.
Int J Infect Dis. 2012 Oct;16(10):e735-8. doi: 10.1016/j.ijid.2012.05.1036. Epub 2012 Jul 26.
2
The role of vitamin D in children with recurrent tonsillopharyngitis.
Ital J Pediatr. 2012 Jun 8;38:25. doi: 10.1186/1824-7288-38-25.
3
Vitamin D levels in children with recurrent tonsillitis.
Int J Pediatr Otorhinolaryngol. 2011 Mar;75(3):364-7. doi: 10.1016/j.ijporl.2010.12.006. Epub 2011 Jan 7.
4
Vitamin D and tonsil disease--preliminary observations.
Int J Pediatr Otorhinolaryngol. 2011 Feb;75(2):261-4. doi: 10.1016/j.ijporl.2010.11.012. Epub 2010 Dec 4.
6
Vitamin D and the immune system: new perspectives on an old theme.
Endocrinol Metab Clin North Am. 2010 Jun;39(2):365-79, table of contents. doi: 10.1016/j.ecl.2010.02.010.
7
Vitamin D, innate immunity and upper respiratory tract infection.
J Laryngol Otol. 2010 May;124(5):465-9. doi: 10.1017/S0022215109992684. Epub 2010 Jan 13.
8
Vitamin D and respiratory health.
Clin Exp Immunol. 2009 Oct;158(1):20-5. doi: 10.1111/j.1365-2249.2009.04001.x.
9
A randomized controlled trial of vitamin D3 supplementation for the prevention of symptomatic upper respiratory tract infections.
Epidemiol Infect. 2009 Oct;137(10):1396-404. doi: 10.1017/S0950268809002404. Epub 2009 Mar 19.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验