Carlin B W, Harrell J H, Olson L K, Moser K M
Department of Medicine, University of California School of Medicine, San Diego.
Chest. 1989 Nov;96(5):1110-4. doi: 10.1378/chest.96.5.1110.
Metastatic disease from colorectal carcinoma to the tracheobronchial tree has previously been reported in only 15 cases. Various modalities of treatment have been attempted but have met with limited success. We describe an additional nine cases, as documented by fiberoptic bronchoscopy, treated by Nd-Yag laser therapy debulking. Improvement in bronchial patency was evidenced visually in each case, and relief of symptoms occurred in eight cases. Survival periods of up to 21 months occurred. This type of metastatic disease may be more common than previously reported and combination therapy to include Nd-Yag laser debulking offers a safe and effective alternative in the palliative management of pulmonary symptoms and increased survival in select patients.
此前仅有15例关于结直肠癌转移至气管支气管树的病例报道。人们尝试了各种治疗方法,但成效有限。我们描述了另外9例经纤维支气管镜检查证实、采用钕钇铝石榴石激光减瘤治疗的病例。每例均可见支气管通畅情况在视觉上得到改善,8例症状得到缓解。生存期长达21个月。这种转移性疾病可能比之前报道的更为常见,包括钕钇铝石榴石激光减瘤的联合治疗为缓解肺部症状及提高部分患者的生存率提供了一种安全有效的替代方法。