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姜黄素在炎症和免疫介导疾病中的治疗作用：一种天然的万能药？

Therapeutic effects of curcumin in inflammatory and immune-mediated diseases: A nature-made jack-of-all-trades?

作者信息

Abdollahi Elham, Momtazi Amir Abbas, Johnston Thomas P, Sahebkar Amirhossein

机构信息

Department of Medical Immunology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Student Research Committee, Mashhad University of Medical Sciences, Mashhad, Iran.

出版信息

J Cell Physiol. 2018 Feb;233(2):830-848. doi: 10.1002/jcp.25778. Epub 2017 Mar 31.

DOI:10.1002/jcp.25778
PMID:28059453
Abstract

Curcumin is a dietary polyphenol from turmeric with numerous pharmacological activities. Novel animal and human studies indicate that curcumin can affect different immune cells, such as various T lymphocyte subsets, macrophages, dendritic cells, B lymphocytes and natural killer cells, which results in decreasing severity of various diseases with immunological etiology. The present review provides a comprehensive overview of the effects of curcumin on different immune cells and immune system-related diseases.

摘要

姜黄素是一种来自姜黄的膳食多酚，具有多种药理活性。新的动物和人体研究表明，姜黄素可影响不同的免疫细胞，如各种T淋巴细胞亚群、巨噬细胞、树突状细胞、B淋巴细胞和自然杀伤细胞，从而降低各种具有免疫病因的疾病的严重程度。本综述全面概述了姜黄素对不同免疫细胞和免疫系统相关疾病的影响。

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