Widmann Gerlig, Bischel Alexander, Stratis Andreas, Bosmans Hilde, Jacobs Reinhilde, Gassner Eva-Maria, Puelacher Wolfgang, Pauwels Ruben
1 Department of Radiology, Innsbruck Medical University, Innsbruck, Austria.
2 Department of Craniomaxillofacial Surgery, Innsbruck Medical University, Innsbruck, Austria.
Dentomaxillofac Radiol. 2017 Apr;46(4):20160452. doi: 10.1259/dmfr.20160452. Epub 2017 Feb 17.
The objective of this study was to determine how iterative reconstruction technology (IRT) influences contrast and spatial resolution in ultralow-dose dentomaxillofacial CT imaging.
A polymethyl methacrylate phantom with various inserts was scanned using a reference protocol (RP) at CT dose index volume 36.56 mGy, a sinus protocol at 18.28 mGy and ultralow-dose protocols (LD) at 4.17 mGy, 2.36 mGy, 0.99 mGy and 0.53 mGy. All data sets were reconstructed using filtered back projection (FBP) and the following IRTs: adaptive statistical iterative reconstructions (ASIRs) (ASIR-50, ASIR-100) and model-based iterative reconstruction (MBIR). Inserts containing line-pair patterns and contrast detail patterns for three different materials were scored by three observers. Observer agreement was analyzed using Cohen's kappa and difference in performance between the protocols and reconstruction was analyzed with Dunn's test at α = 0.05.
Interobserver agreement was acceptable with a mean kappa value of 0.59. Compared with the RP using FBP, similar scores were achieved at 2.36 mGy using MBIR. MIBR reconstructions showed the highest noise suppression as well as good contrast even at the lowest doses. Overall, ASIR reconstructions did not outperform FBP.
LD and MBIR at a dose reduction of >90% may show no significant differences in spatial and contrast resolution compared with an RP and FBP. Ultralow-dose CT and IRT should be further explored in clinical studies.
本研究的目的是确定迭代重建技术(IRT)如何影响超低剂量牙颌面CT成像中的对比度和空间分辨率。
使用参考方案(RP)在CT剂量指数体积为36.56 mGy时、鼻窦方案在18.28 mGy时以及超低剂量方案(LD)在4.17 mGy、2.36 mGy、0.99 mGy和0.53 mGy时,对带有各种插入物的聚甲基丙烯酸甲酯体模进行扫描。所有数据集均使用滤波反投影(FBP)以及以下IRT进行重建:自适应统计迭代重建(ASIR)(ASIR-50、ASIR-100)和基于模型的迭代重建(MBIR)。由三名观察者对包含三种不同材料的线对图案和对比度细节图案的插入物进行评分。使用科恩kappa分析观察者间的一致性,并使用α = 0.05的邓恩检验分析各方案与重建之间的性能差异。
观察者间的一致性可接受,平均kappa值为0.59。与使用FBP的RP相比,使用MBIR在2.36 mGy时获得了相似的分数。即使在最低剂量下,MBR重建也显示出最高的噪声抑制以及良好的对比度。总体而言,ASIR重建并未优于FBP。
与RP和FBP相比,剂量降低>90%的LD和MBIR在空间和对比度分辨率方面可能没有显著差异。超低剂量CT和IRT应在临床研究中进一步探索。