Department of Oral Health Sciences, University of Leuven, Leuven, Belgium.
Br J Radiol. 2013 Jan;86(1021):20120135. doi: 10.1259/bjr.20120135.
The aim of this study was to investigate the use of dental cone beam CT (CBCT) grey values for density estimations by calculating the correlation with multislice CT (MSCT) values and the grey value error after recalibration.
A polymethyl methacrylate (PMMA) phantom was developed containing inserts of different density: air, PMMA, hydroxyapatite (HA) 50 mg cm(-3), HA 100, HA 200 and aluminium. The phantom was scanned on 13 CBCT devices and 1 MSCT device. Correlation between CBCT grey values and CT numbers was calculated, and the average error of the CBCT values was estimated in the medium-density range after recalibration.
Pearson correlation coefficients ranged between 0.7014 and 0.9996 in the full-density range and between 0.5620 and 0.9991 in the medium-density range. The average error of CBCT voxel values in the medium-density range was between 35 and 1562.
Even though most CBCT devices showed a good overall correlation with CT numbers, large errors can be seen when using the grey values in a quantitative way. Although it could be possible to obtain pseudo-Hounsfield units from certain CBCTs, alternative methods of assessing bone tissue should be further investigated.
The suitability of dental CBCT for density estimations was assessed, involving a large number of devices and protocols. The possibility for grey value calibration was thoroughly investigated.
本研究旨在通过计算与多层 CT(MSCT)值的相关性以及重新校准后的灰度值误差,来研究牙用锥形束 CT(CBCT)灰度值在密度估计中的应用。
研制了一种包含不同密度嵌体的聚甲基丙烯酸甲酯(PMMA)体模:空气、PMMA、羟磷灰石(HA)50mg·cm(-3)、HA 100、HA 200 和铝。对 13 台 CBCT 设备和 1 台 MSCT 设备进行了扫描。计算了 CBCT 灰度值与 CT 值之间的相关性,并在重新校准后估计了中密度范围内的 CBCT 值的平均误差。
在全密度范围内,Pearson 相关系数范围为 0.7014 至 0.9996,在中密度范围内,Pearson 相关系数范围为 0.5620 至 0.9991。中密度范围内 CBCT 体素值的平均误差在 35 至 1562 之间。
尽管大多数 CBCT 设备与 CT 数值之间表现出良好的总体相关性,但在定量使用灰度值时会出现较大误差。虽然某些 CBCT 可能可以获得伪亨氏单位,但应进一步研究替代的骨组织评估方法。
评估了牙用 CBCT 进行密度估计的适用性,涉及大量设备和方案。彻底研究了灰度值校准的可能性。