Kim So Young, Bang Woojin, Kim Min-Su, Park Bumjung, Kim Jin-Hwan, Choi Hyo Geun
Department of Otorhinolaryngology-Head & Neck Surgery and Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea.
Department of Urology, Hallym University Sacred Heart Hospital, Hallym University Sacred Heart Hospital, Anyang, Korea.
PLoS One. 2017 Jan 6;12(1):e0169690. doi: 10.1371/journal.pone.0169690. eCollection 2017.
Several reports have demonstrated associations between falls and nocturia in the elderly. However, little information is available regarding other age groups. This study evaluated the relationship between the frequency of nocturia and falls in men using a large, population-based survey in Korea, and the results were adjusted for various confounding factors. Data from a 2011 Korean community health survey (KCHS) were retrieved for 92,660 men aged 19 to 103 years. Information regarding the history of slips or falls in the past year was collected. The frequency of nocturia was classified as 0, 1, 2, 3, 4, and ≥ 5 instances a night. Walking during the day, education, income, body mass index (BMI), smoking, alcohol consumption, sleep time, stress level and medical histories of hypertension, diabetes mellitus, hyperlipidemia, cerebral stroke, angina or myocardial infarction, arthritis, and osteoporosis were adjusted using multiple logistic regression analysis with complex sampling. A subgroup analysis was conducted for young (19-30 years), middle-aged (31-60 years), and elderly individuals (61+ years). Approximately 14.6% of the men had a history of falls. Their mean age was 42.9 years, which was significantly higher than that of the non-faller group (P < 0.001). An increased frequency of nocturia was associated with increased adjusted odds ratio (AOR) for falls (AOR for 1 instance of nocturia/night = 1.41 [95% confidence interval, 1.33-1.50]; AOR for 2 instances = 1.41 [1.33-1.50]; AOR for 3 instances = 2.00 [1.75-2.28]; AOR for 4 instances = 2.12 [1.73-2.61]; AOR for ≥ 5 instances = 2.02 [1.74-2.36], P < 0.001). In the subgroup analysis, the AORs for falls significantly increased in all age groups as the frequency of nocturia increased.
几份报告已证明老年人跌倒与夜尿症之间存在关联。然而，关于其他年龄组的信息却很少。本研究利用韩国一项基于人群的大型调查评估了男性夜尿频率与跌倒之间的关系，并针对各种混杂因素对结果进行了调整。从2011年韩国社区健康调查（KCHS）中检索了92660名年龄在19至103岁之间男性的数据。收集了过去一年中滑倒或跌倒史的相关信息。夜尿频率分为每晚0次、1次、2次、3次、4次和≥5次。利用复杂抽样的多重逻辑回归分析对白天行走情况、教育程度、收入、体重指数（BMI）、吸烟、饮酒、睡眠时间、压力水平以及高血压、糖尿病、高脂血症、脑卒、心绞痛或心肌梗死、关节炎和骨质疏松症的病史进行了调整。对年轻人（19 - 30岁）、中年人（31 - 60岁）和老年人（61岁及以上）进行了亚组分析。约14.6%的男性有跌倒史。他们的平均年龄为42.9岁，显著高于未跌倒组（P < 0.001）。夜尿频率增加与跌倒的调整后比值比（AOR）升高相关（每晚夜尿1次的AOR = 1.41 [95%置信区间，1.33 - 1.50]；夜尿2次的AOR = 1.41 [1.33 - 1.50]；夜尿3次的AOR = 2.00 [1.75 - 2.28]；夜尿4次的AOR = 2.12 [1.73 - 2.61]；夜尿≥5次的AOR = 2.02 [1.74 - 2.36]，P < 0.001）。在亚组分析中，随着夜尿频率增加，所有年龄组跌倒的AOR均显著升高。
