Krops Leonie A, Jaarsma Eva A, Dijkstra Pieter U, Geertzen Jan H B, Dekker Rienk
University of Groningen, University Medical Center Groningen, Department of Rehabilitation Medicine, Groningen, The Netherlands.
University of Groningen, University Medical Center Groningen, Department of Oral and Maxillofacial Surgery, Groningen, The Netherlands.
PLoS One. 2017 Jan 6;12(1):e0169169. doi: 10.1371/journal.pone.0169169. eCollection 2017.
To establish reference values for Health Related Quality of Life (HRQoL) in a Dutch rehabilitation population, and to study effects of patient characteristics, diagnosis and physical activity on HRQoL in this population.
Former rehabilitation patients (3169) were asked to fill in a questionnaire including the Dutch version of the RAND-36. Differences between our rehabilitation patients and Dutch reference values were analyzed (t-tests). Effects of patient characteristics, diagnosis and movement intensity on scores on the subscales of the RAND-36 were analyzed using block wise multiple regression analyses.
In total 1223 patients (39%) returned the questionnaire. HRQoL was significantly poorer in the rehabilitation patients compared to Dutch reference values on all subscales (p<0.001) except for health change (p = 0.197). Longer time between questionnaire and last treatment was associated with a smaller health change (p = 0.035). Higher age negatively affected physical functioning (p<0.001), social functioning (p = 0.004) and health change (p = 0.001). Diagnosis affected outcomes on all subscales except role limitations physical, and mental health (p ranged <0.001 to 0.643). Higher movement intensity was associated with better outcomes on all subscales except for mental health (p ranged <0.001 to 0.190).
HRQoL is poorer in rehabilitation patients compared to Dutch reference values. Physical components of HRQoL are affected by diagnosis. In rehabilitation patients an association between movement intensity and HRQoL was found. For clinical purposes, results of this study can be used as reference values for HRQoL in a rehabilitation setting.
建立荷兰康复人群健康相关生活质量（HRQoL）的参考值，并研究患者特征、诊断和身体活动对该人群HRQoL的影响。
邀请3169名曾接受康复治疗的患者填写一份包含荷兰版RAND-36的问卷。分析我们的康复患者与荷兰参考值之间的差异（t检验）。使用逐步多元回归分析来分析患者特征、诊断和运动强度对RAND-36各子量表得分的影响。
共有1223名患者（39%）返回了问卷。除健康变化（p = 0.197）外，康复患者在所有子量表上的HRQoL均显著低于荷兰参考值（p<0.001）。问卷填写时间与最后一次治疗时间间隔越长，健康变化越小（p = 0.035）。较高的年龄对身体功能（p<0.001）、社会功能（p = 0.004）和健康变化（p = 0.001）有负面影响。诊断对除身体角色限制和心理健康外的所有子量表结果均有影响（p值范围为<0.001至0.643）。除心理健康外，较高的运动强度与所有子量表上更好的结果相关（p值范围为<0.001至0.190）。
与荷兰参考值相比，康复患者的HRQoL较差。HRQoL的身体组成部分受诊断影响。在康复患者中发现了运动强度与HRQoL之间的关联。出于临床目的，本研究结果可作为康复环境中HRQoL的参考值。
