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盐酸增强型射频消融治疗自发性破裂的大肝细胞癌：一例报告

Hydrochloric acid-enhanced radiofrequency ablation for treating a large hepatocellular carcinoma with spontaneous rapture: a case report.

作者信息

Huang Jin-Hua, Morelli John N, Ai Fei, Zou Ru-Hai, Gu Yang-Kui, Gao Fei, Zhang Tian-Qi, Yao Wang, Jiang Xiong-Ying, Zhang Yan-Yang

机构信息

Department of Minimally Invasive Interventional Therapy, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, 510060, Guangdong, P. R. China.

Department of Interventional Radiology, St. John's Medical Center, Tulsa, OK, 74131, USA.

出版信息

Chin J Cancer. 2017 Jan 7;36(1):1. doi: 10.1186/s40880-016-0161-8.

DOI:10.1186/s40880-016-0161-8
PMID:28061892
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5219733/
Abstract

BACKGROUND

A ruptured hepatocellular carcinoma (HCC) is often fatal. In addition to surgery and transarterial embolization, radiofrequency ablation (RFA) might be another option for treating a ruptured HCC. Unfortunately, conventional RFA has a limited ablation zone; as such, it is rarely used to treat ruptured tumors.

CASE PRESENTATION

This case was a 60-year-old man who had a large, ruptured HCC in which hydrochloric acid (HCl)-enhanced RFA successfully controlled the bleeding and made the tumor completely necrotic.

CONCLUSION

Considering the effectiveness of HCl-enhanced RFA in achieving hemostasis and tumor ablation, it might be a new option for treating large, ruptured HCCs.

摘要

背景

肝细胞癌（HCC）破裂通常是致命的。除手术和经动脉栓塞外，射频消融（RFA）可能是治疗破裂HCC的另一种选择。不幸的是，传统RFA的消融区域有限；因此，它很少用于治疗破裂的肿瘤。

病例报告

该病例为一名60岁男性，患有巨大的破裂HCC，盐酸（HCl）增强型RFA成功控制了出血并使肿瘤完全坏死。

结论

考虑到HCl增强型RFA在实现止血和肿瘤消融方面的有效性，它可能是治疗巨大破裂HCC的一种新选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a4c/5219733/2e57c8d76928/40880_2016_161_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a4c/5219733/fb84abb11248/40880_2016_161_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a4c/5219733/93a3d2ab6ac5/40880_2016_161_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a4c/5219733/2fef1fd895da/40880_2016_161_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a4c/5219733/7390c17c6abf/40880_2016_161_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a4c/5219733/2e57c8d76928/40880_2016_161_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a4c/5219733/fb84abb11248/40880_2016_161_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a4c/5219733/93a3d2ab6ac5/40880_2016_161_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a4c/5219733/2fef1fd895da/40880_2016_161_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a4c/5219733/7390c17c6abf/40880_2016_161_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a4c/5219733/2e57c8d76928/40880_2016_161_Fig5_HTML.jpg

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本文引用的文献

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Ex Vivo Liver Experiment of Hydrochloric Acid-Infused and Saline-Infused Monopolar Radiofrequency Ablation: Better Outcomes in Temperature, Energy, and Coagulation.盐酸注入和生理盐水注入单极射频消融的离体肝脏实验：在温度、能量和凝血方面有更好的结果
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Management of spontaneously ruptured hepatocellular carcinomas in the radiofrequency ablation era.
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