Pagani Matteo, Tasca Carla, De Vincenti Rosita, Fedi Massimo
General Surgery, University of Florence, Florence, ITA.
Hepatobiliary Surgery, USL Toscana Centro, Pistoia, ITA.
Cureus. 2024 Nov 27;16(11):e74585. doi: 10.7759/cureus.74585. eCollection 2024 Nov.
Spontaneous liver bleeding is a rare but life-threatening complication of hepatocellular carcinoma (HCC). The optimal management strategy for this condition remains a topic of ongoing debate. We present the case of a 74-year-old man with cirrhosis and hemorrhagic shock resulting from the spontaneous rupture of HCC. Following a contrast-enhanced CT scan, the patient underwent emergency laparotomy. Hemostasis was attempted using conventional techniques but was unsuccessful. Due to unstable conditions (low blood pressure and high heart rate), poor liver function reserve, and a multifocal tumor, we decided to perform ultrasound-guided radiofrequency ablation (RFA) to achieve hemostasis. The patient was admitted to the ICU for early postoperative monitoring. On the second postoperative day, the patient returned to the surgical department. In most cases, interventional treatment is necessary to achieve hemostasis, even in patients with Child-Pugh C liver function. While transarterial chemoembolization followed by staged hepatectomy is considered the treatment of choice based on current clinical evidence, RFA is a viable alternative. In this case report, we demonstrate that RFA is a safe and effective technique for achieving hemostasis. It should be considered as an option for selected patients with ruptured HCC who are hemodynamically unstable, when embolization or resection is unavailable or unfeasible due to the patient's condition, or in cases of end-stage liver disease.
自发性肝出血是肝细胞癌(HCC)一种罕见但危及生命的并发症。针对这种情况的最佳治疗策略仍是一个持续争论的话题。我们报告一例74岁男性患者,患有肝硬化,因HCC自发性破裂导致失血性休克。在进行增强CT扫描后,患者接受了急诊剖腹手术。尝试使用传统技术止血但未成功。由于病情不稳定(低血压和高心率)、肝功能储备差以及肿瘤多灶性,我们决定进行超声引导下射频消融(RFA)以实现止血。患者被收入重症监护病房进行术后早期监测。术后第二天,患者返回外科。在大多数情况下,即使是Child-Pugh C级肝功能的患者,也需要进行介入治疗来实现止血。虽然根据目前的临床证据,经动脉化疗栓塞术随后分期肝切除术被认为是首选治疗方法,但RFA是一种可行的替代方法。在本病例报告中,我们证明RFA是一种实现止血的安全有效技术。对于因患者病情导致栓塞或切除不可用或不可行的血流动力学不稳定的HCC破裂患者,或终末期肝病患者,应将其视为一种选择。