Loos Helene M, Doucet Sébastien, Védrines Fanny, Sharapa Constanze, Soussignan Robert, Durand Karine, Sagot Paul, Buettner Andrea, Schaal Benoist
Developmental Ethology and Cognitive Psychology Group, Centre des Sciences du Goût et de l'Alimentation, CNRS-Université de Bourgogne, 9E bd Jeanne d'Arc, 21000, Dijon, France.
Department of Chemistry and Pharmacy, Emil Fischer Center, Friedrich-Alexander Universität Erlangen-Nürnberg, Henkestraße 9, 91054, Erlangen, Germany.
J Chem Ecol. 2017 Jan;43(1):106-117. doi: 10.1007/s10886-016-0804-x. Epub 2017 Jan 6.
Conjugated forms of odorants contributing to sweat odor occur not only in human sweat but also in amniotic fluid, colostrum, and milk. However, it is unclear whether the released odorants are detected and hedonically discriminated by human newborns. To investigate this issue, we administered highly diluted solutions of (R)/(S)-3-methyl-3-sulfanylhexan-1-ol (MSH), (R)/(S)-3-sulfanylhexan-1-ol (SH), (E)/(Z)-3-methylhex-2-enoic acid (3M2H), and (R)/(S)-3-hydroxy-3-methylhexanoic acid (HMHA) to 3-d-old infants while their respiratory rate and oro-facial movements were recorded. Adult sensitivity to these odorants was assessed via triangle tests. Whereas no neonatal stimulus-specific response was found for respiratory rate, oro-facial reactivity indicated orthonasal detection of MSH and SH by male neonates, and of HMHA by the whole group of neonates. Dependent on the dilution of odorants, newborns evinced neutral responses or longer negative oro-facial expressions compared with the reference stimuli. Finally, newborns appeared to be more sensitive to the target odorants than did adults.
导致汗味的共轭形式的气味剂不仅存在于人类汗液中，也存在于羊水、初乳和乳汁中。然而，尚不清楚释放出的气味剂是否能被人类新生儿察觉并产生愉悦或不悦的区分。为了研究这个问题，我们给3日龄的婴儿施用了高度稀释的（R）/（S）-3-甲基-3-巯基己醇（MSH）、（R）/（S）-3-巯基己醇（SH）、（E）/（Z）-3-甲基己-2-烯酸（3M2H）和（R）/（S）-3-羟基-3-甲基己酸（HMHA）溶液，同时记录他们的呼吸频率和口面部运动。通过三角试验评估成年人对这些气味剂的敏感度。虽然未发现呼吸频率有新生儿刺激特异性反应，但口面部反应表明雄性新生儿能通过鼻前嗅觉检测到MSH和SH，而整个新生儿群体能检测到HMHA。根据气味剂的稀释程度，与参考刺激相比，新生儿表现出中性反应或更长时间的负面口面部表情。最后，新生儿似乎比成年人对目标气味剂更敏感。
