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接受伤口护理患者中粘质沙雷氏菌引起的伤口及软组织感染:一起与医疗保健相关的暴发疫情

Wound and soft tissue infections of Serratia marcescens in patients receiving wound care: A health care-associated outbreak.

作者信息

Us Ebru, Kutlu Huseyin H, Tekeli Alper, Ocal Duygu, Cirpan Sevilay, Memikoglu Kemal O

机构信息

Central Clinical Microbiology Laboratory, Ibni Sina Hospital, Ankara University Faculty of Medicine, Ankara, Turkey; Clinical Microbiology Department, Ankara University Faculty of Medicine, Ankara, Turkey.

Clinical Microbiology Laboratory, Mus State Hospital, Mus, Turkey.

出版信息

Am J Infect Control. 2017 Apr 1;45(4):443-447. doi: 10.1016/j.ajic.2016.11.015. Epub 2017 Jan 4.

Abstract

We described a health care-associated Serratia marcescens outbreak of wound and soft tissue infection lasting approximately 11 months at Ankara University Ibni Sina Hospital. After identification of S marcescens strains from the clinical and environmental samples, and their susceptibility testing to antimicrobial agents, pulsed-field gel electrophoresis (PFGE) was performed to detect molecular epidemiologic relationships among these isolates. The strains which were isolated from the saline bottles used for wound cleansing in the wound care unit were found to be 100% interrelated by PFGE to the strains from the samples of the outbreak patients. Reuse of the emptied bottles has no longer been allowed since the outbreak occurred. Besides, more efficient and frequent infection control training for hospital staff has been conducted.

摘要

我们描述了在安卡拉大学伊本·西那医院发生的一起与医疗保健相关的粘质沙雷氏菌伤口及软组织感染暴发事件,该事件持续了约11个月。从临床和环境样本中鉴定出粘质沙雷氏菌菌株并对其进行抗菌药物敏感性测试后,采用脉冲场凝胶电泳(PFGE)检测这些分离株之间的分子流行病学关系。结果发现,从伤口护理单元用于伤口清洁的盐水瓶中分离出的菌株,通过PFGE与暴发患者样本中的菌株100%相关。自暴发事件发生后,已不再允许重复使用空瓶。此外,还对医院工作人员开展了更有效、更频繁的感染控制培训。

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