Gopalan Mohan Roy, Karunakaran Vidhukumar, Prabhakaran Anil, Jayakumar Krishnannair Lalithamma
Department of Psychiatry, Government Medical College, Trivandrum, Kerala, India.
Department of Radiotherapy, Government Medical College, Trivandrum, Kerala, India.
Indian J Psychiatry. 2016 Jul-Sep;58(3):275-280. doi: 10.4103/0019-5545.191995.
To study the prevalence of Psychiatric disorders in cancer patients and to find out the factors associated with Psychiatric disorders in Cancer Patients.
Department of Radiotherapy, Medical College, Thiruvananthapuram, cross sectional survey design was used.
Adult patients (18 years of age and above), having a diagnosis of carcinoma were selected by consecutive sampling method.A questionnaire which included back ground data, socio economic variables, treatment variables like type of malignancy, exposure to radiation & chemotherapy prior to the evaluation and current treatment, co occurring medical illness & treatment and past & family history of psychiatric illness was used to collect data. Delirium rating scale and MINI International neuropsychiatric interview were used to assess Psychiatric disorders and delirium.
Chi square and logistics regression tests were used for analysis.
Of the 384 assessed, 160(41.7%) had psychiatric disorders. Adjustment disorders were seen in 22.6%. 10.9% of subjects had major depressive disorder. Thus a total of 33.5% of patients had a diagnosis of either anxiety or depressive disorder. Proportion of patients having delirium was 6.5%. Hypomania was seen in small (1.6%) of patients. Multivariate analysis for various parameters for psychiatric disorders showed that age, past history of chemotherapy, past history of radiotherapy, & surgical treatment of carcinomas are significant predictors of psychiatric disorders.
Psychiatric disorders are seen in a significant proportion of Psychiatric patients.
研究癌症患者精神障碍的患病率,并找出与癌症患者精神障碍相关的因素。
采用横断面调查设计,地点为特里凡得琅医学院放疗科。
通过连续抽样法选取成年(18岁及以上)癌症患者。使用一份问卷收集数据,问卷内容包括背景资料、社会经济变量、治疗变量(如恶性肿瘤类型、评估前接受的放疗和化疗以及当前治疗)、并发的内科疾病及治疗情况以及精神疾病的既往史和家族史。使用谵妄评定量表和MINI国际神经精神访谈来评估精神障碍和谵妄。
采用卡方检验和逻辑回归检验进行分析。
在384名接受评估的患者中,160名(41.7%)患有精神障碍。其中,适应障碍患者占22.6%。10.9%的受试者患有重度抑郁症。因此,共有33.5%的患者被诊断为焦虑或抑郁障碍。谵妄患者的比例为6.5%。轻度躁狂在少数(1.6%)患者中出现。对精神障碍的各种参数进行多变量分析显示,年龄、既往化疗史、既往放疗史以及癌症的手术治疗是精神障碍的重要预测因素。
相当一部分癌症患者存在精神障碍。