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癌症患者精神疾病患病率——基于医院的横断面调查。

Prevalence of psychiatric morbidity among cancer patients - hospital-based, cross-sectional survey.

作者信息

Gopalan Mohan Roy, Karunakaran Vidhukumar, Prabhakaran Anil, Jayakumar Krishnannair Lalithamma

机构信息

Department of Psychiatry, Government Medical College, Trivandrum, Kerala, India.

Department of Radiotherapy, Government Medical College, Trivandrum, Kerala, India.

出版信息

Indian J Psychiatry. 2016 Jul-Sep;58(3):275-280. doi: 10.4103/0019-5545.191995.

Abstract

AIM

To study the prevalence of Psychiatric disorders in cancer patients and to find out the factors associated with Psychiatric disorders in Cancer Patients.

SETTINGS AND DESIGN

Department of Radiotherapy, Medical College, Thiruvananthapuram, cross sectional survey design was used.

METHODS AND MATERIAL

Adult patients (18 years of age and above), having a diagnosis of carcinoma were selected by consecutive sampling method.A questionnaire which included back ground data, socio economic variables, treatment variables like type of malignancy, exposure to radiation & chemotherapy prior to the evaluation and current treatment, co occurring medical illness & treatment and past & family history of psychiatric illness was used to collect data. Delirium rating scale and MINI International neuropsychiatric interview were used to assess Psychiatric disorders and delirium.

STATISTICAL ANALYSIS USED

Chi square and logistics regression tests were used for analysis.

RESULTS

Of the 384 assessed, 160(41.7%) had psychiatric disorders. Adjustment disorders were seen in 22.6%. 10.9% of subjects had major depressive disorder. Thus a total of 33.5% of patients had a diagnosis of either anxiety or depressive disorder. Proportion of patients having delirium was 6.5%. Hypomania was seen in small (1.6%) of patients. Multivariate analysis for various parameters for psychiatric disorders showed that age, past history of chemotherapy, past history of radiotherapy, & surgical treatment of carcinomas are significant predictors of psychiatric disorders.

CONCLUSIONS

Psychiatric disorders are seen in a significant proportion of Psychiatric patients.

摘要

目的

研究癌症患者精神障碍的患病率,并找出与癌症患者精神障碍相关的因素。

设置与设计

采用横断面调查设计,地点为特里凡得琅医学院放疗科。

方法与材料

通过连续抽样法选取成年(18岁及以上)癌症患者。使用一份问卷收集数据,问卷内容包括背景资料、社会经济变量、治疗变量(如恶性肿瘤类型、评估前接受的放疗和化疗以及当前治疗)、并发的内科疾病及治疗情况以及精神疾病的既往史和家族史。使用谵妄评定量表和MINI国际神经精神访谈来评估精神障碍和谵妄。

所用统计分析方法

采用卡方检验和逻辑回归检验进行分析。

结果

在384名接受评估的患者中,160名(41.7%)患有精神障碍。其中,适应障碍患者占22.6%。10.9%的受试者患有重度抑郁症。因此,共有33.5%的患者被诊断为焦虑或抑郁障碍。谵妄患者的比例为6.5%。轻度躁狂在少数(1.6%)患者中出现。对精神障碍的各种参数进行多变量分析显示,年龄、既往化疗史、既往放疗史以及癌症的手术治疗是精神障碍的重要预测因素。

结论

相当一部分癌症患者存在精神障碍。

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