Zhou Jian, Yang Fan, Jiang Guanchao, Wang Jun
Department of Thoracic Surgery, Peking University People's Hospital, Beijing 100044, China.
J Thorac Dis. 2016 Oct;8(Suppl 9):S738-S743. doi: 10.21037/jtd.2016.09.49.
Near-infrared (NIR) fluorescence guided surgery is an emerging technique. This technique uses the combination of dyes and NIR imaging devices to expand the visible spectrum. Thus it can provide more anatomic and functional information, and may facilitate a more complete resection of cancer, or better protection of important normal structures. Recently, significant progress has been made in the field of NIR fluorescence guided thoracic surgery. This may lead to better prognosis and health-economic outcomes. In this article, the current studies of indocyanine green (ICG) based NIR fluorescence guided thoracic surgeries are reviewed. The applications are classified into four categories, which are applications based on blood supply, lymphatic drainage, the enhanced permeability and retention (EPR) effect, and the other mechanisms.
近红外（NIR）荧光引导手术是一种新兴技术。该技术利用染料和近红外成像设备的组合来扩展可见光谱。因此，它可以提供更多的解剖和功能信息，并可能有助于更彻底地切除癌症，或更好地保护重要的正常结构。最近，近红外荧光引导胸外科领域取得了重大进展。这可能会带来更好的预后和健康经济结果。在本文中，对基于吲哚菁绿（ICG）的近红外荧光引导胸外科手术的当前研究进行了综述。其应用分为四类，即基于血液供应、淋巴引流、增强渗透和滞留（EPR）效应以及其他机制的应用。
