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微通道中的颗粒积累及其通过表面驻波(SSAW)的减少。

Particle Accumulation in a Microchannel and Its Reduction by a Standing Surface Acoustic Wave (SSAW).

作者信息

Sriphutkiat Yannapol, Zhou Yufeng

机构信息

School of Mechanical and Aerospace Engineering, Nanyang Technological University, 50 Nanyang Ave., Singapore Centre for 3D Printing (SC3DP), Singapore 639798, Singapore.

出版信息

Sensors (Basel). 2017 Jan 7;17(1):106. doi: 10.3390/s17010106.

DOI:10.3390/s17010106
PMID:28067852
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5298679/
Abstract

Accumulation of particles in a high concentration on a microchannel wall is a common phenomenon in a colloidal fluid. Gradual accumulation/deposition of particles can eventually obstruct the fluid flow and lead to clogging, which seriously affects the accuracy and reliability of nozzle-based printing and causes damage to the nozzle. Particle accumulation in a 100 μm microchannel was investigated by light microscopy, and its area growth in an exponential format was used to quantify this phenomenon. The effects of the constriction angle and alginate concentration on particle accumulation were also studied. In order to reduce the clogging problem, an acoustic method was proposed and evaluated here. Numerical simulation was first conducted to predict the acoustic radiation force on the particles in the fluid with different viscosities. Interdigital transducers (IDTs) were fabricated on the LiNbO₃ wafer to produce standing surface acoustic waves (SSAW) in the microchannel. It was found that the actuation of SSAW can reduce the accumulation area in the microchannel by 2 to 3.7-fold. In summary, the particle accumulation becomes significant with the increase of the constriction angle and fluid viscosity. The SSAW can effectively reduce the particle accumulation and postpone clogging.

摘要

在微通道壁上高浓度地积累颗粒是胶体流体中的常见现象。颗粒的逐渐积累/沉积最终会阻碍流体流动并导致堵塞,这严重影响基于喷嘴的打印的准确性和可靠性,并对喷嘴造成损坏。通过光学显微镜研究了100μm微通道中的颗粒积累情况,并以指数形式的面积增长来量化这一现象。还研究了收缩角和藻酸盐浓度对颗粒积累的影响。为了减少堵塞问题,本文提出并评估了一种声学方法。首先进行了数值模拟,以预测不同粘度流体中颗粒上的声辐射力。在LiNbO₃晶片上制作了叉指换能器(IDT),以在微通道中产生表面驻波(SSAW)。结果发现,SSAW的作用可使微通道中的积累面积减少2至3.7倍。总之,随着收缩角和流体粘度的增加,颗粒积累变得显著。SSAW可以有效减少颗粒积累并延缓堵塞。

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2
Rapid formation of size-controllable multicellular spheroids via 3D acoustic tweezers.通过 3D 声镊快速形成可控制大小的多细胞球体。
Lab Chip. 2016 Jul 5;16(14):2636-43. doi: 10.1039/c6lc00444j.
3
Rotational manipulation of single cells and organisms using acoustic waves.利用声波对单细胞和生物体进行旋转操作。
Biosensors (Basel). 2021 Nov 22;11(11):470. doi: 10.3390/bios11110470.
4
Prevention of Microsphere Blockage in Catheter Tubes Using Convex Air Bubbles.使用凸形气泡预防导管中的微球堵塞
Micromachines (Basel). 2020 Nov 27;11(12):1040. doi: 10.3390/mi11121040.
5
Formation of cell spheroids using Standing Surface Acoustic Wave (SSAW).利用驻波表面声波(SSAW)形成细胞球体。
Int J Bioprint. 2017 Jan 17;4(1):130. doi: 10.18063/IJB.v4i1.130. eCollection 2018.
6
Continuous Ultrasonic Reactors: Design, Mechanism and Application.连续式超声反应器:设计、机理与应用
Materials (Basel). 2020 Jan 11;13(2):344. doi: 10.3390/ma13020344.
Nat Commun. 2016 Mar 23;7:11085. doi: 10.1038/ncomms11085.
4
Three-dimensional manipulation of single cells using surface acoustic waves.利用表面声波对单细胞进行三维操控。
Proc Natl Acad Sci U S A. 2016 Feb 9;113(6):1522-7. doi: 10.1073/pnas.1524813113. Epub 2016 Jan 25.
5
Colloidal Jamming Dynamics in Microchannel Bottlenecks.微通道瓶颈中的胶体堵塞动力学
Langmuir. 2016 Feb 16;32(6):1478-88. doi: 10.1021/acs.langmuir.5b04218. Epub 2016 Feb 1.
6
Single Layer Deposition of Polystyrene Particles onto Planar Polydimethylsiloxane Substrates.将聚苯乙烯颗粒单层沉积到平面聚二甲基硅氧烷基片材上。
Langmuir. 2016 Jan 12;32(1):88-101. doi: 10.1021/acs.langmuir.5b02914. Epub 2015 Dec 24.
7
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Adv Mater. 2016 Jan 27;28(4):677-84. doi: 10.1002/adma.201503310. Epub 2015 Nov 26.
8
Two-dimensional single-cell patterning with one cell per well driven by surface acoustic waves.由表面声波驱动的二维单细胞图案化,每孔一个细胞。
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9
Numerical study of acoustophoretic motion of particles in a PDMS microchannel driven by surface acoustic waves.表面声波驱动的聚二甲基硅氧烷微通道中粒子声泳运动的数值研究
Lab Chip. 2015 Jun 21;15(12):2700-9. doi: 10.1039/c5lc00231a.
10
Cell separation using tilted-angle standing surface acoustic waves.使用倾斜角驻波表面声波进行细胞分离。
Proc Natl Acad Sci U S A. 2014 Sep 9;111(36):12992-7. doi: 10.1073/pnas.1413325111. Epub 2014 Aug 25.