Flejou J F, Potet F, Bernades P
Service d'Anatomie Pathologique, Hôpital Beaujon, Clichy.
Gastroenterol Clin Biol. 1989 Aug-Sep;13(8-9):731-3.
We report a case of subacute pancreatitis in a 26-year-old woman, who underwent partial pancreatectomy after a two-week history of abdominal pain. The patient had a long history of allergy. She did not show any well recognized cause of acute or chronic pancreatitis. This patient was thought to have eosinophilic pancreatitis because of the presence of a prominent eosinophilic infiltrate in the resected pancreas. Eosinophilic infiltration of the pancreas has been reported very rarely in the literature, and is usually associated with more generalized disease. In our case there was no extrapancreatic involvement, as shown by repeatedly normal blood eosinophil counts, and by histologically normal spleen, celiac lymph nodes, and gastroduodenal biopsies. We suggest that an allergic mechanism might be responsible for this patient's disease, based on past history of allergic manifestations and the important increase in her serum IgE.
我们报告一例26岁女性的亚急性胰腺炎病例，该患者在腹痛两周后接受了部分胰腺切除术。患者有长期过敏史。她未显示出任何公认的急慢性胰腺炎病因。由于切除的胰腺中存在显著的嗜酸性粒细胞浸润，该患者被认为患有嗜酸性粒细胞性胰腺炎。胰腺的嗜酸性粒细胞浸润在文献中报道极少，且通常与更广泛的疾病相关。在我们的病例中，反复的血液嗜酸性粒细胞计数正常，脾脏、腹腔淋巴结和胃十二指肠活检组织学正常，表明无胰腺外受累。基于患者过去的过敏表现病史以及血清IgE的显著升高，我们认为过敏机制可能是该患者疾病的病因。
