葡萄牙急性Q热的临床表现与诊断——病例系列
Presentation and diagnosis of acute Q fever in Portugal - A case series.
作者信息
Alves Joana, Almeida Francisco, Duro Raquel, Ferraz Rita, Silva Susana, Sobrinho-Simões Joana, Sarmento António
机构信息
Infectious Diseases Department, Centro Hospitalar de São João, Alameda Prof. Hernâni Monteiro, Porto, Portugal; Instituto de Inovação e Investigação em Saúde (I3S), Grupo de I&D em Nefrologia e Doenças Infeciosas, Instituto Nacional de Engenharia Biomédica (INEB), Porto, Portugal.
Clinical Pathology Department, Centro Hospitalar de São João, Alameda Prof. Hernâni Monteiro, Porto, Portugal.
出版信息
IDCases. 2016 Dec 14;7:34-37. doi: 10.1016/j.idcr.2016.11.002. eCollection 2017.
Q fever is a worldwide zoonotic infection caused by the obligate intracellular bacterium that can course with acute or chronic disease. This series describes 7 cases of acute Q fever admitted in a Portuguese University Hospital between 2014 and 2015. All cases presented with hepatitis and had epidemiological history. Diagnosis was done by PCR on majority (5) and by serology and PCR in only 2. Serological tests can be negative in the initial period of the disease. Molecular biology methods by polymerase chain-reaction are extremely important in acute disease, allowing timely diagnosis and treatment.
Q热是一种由专性细胞内细菌引起的全球性人畜共患感染病，可导致急性或慢性疾病。本系列描述了2014年至2015年期间在一家葡萄牙大学医院收治的7例急性Q热病例。所有病例均表现为肝炎且有流行病学史。多数病例（5例）通过聚合酶链反应（PCR）诊断，仅2例通过血清学和PCR诊断。血清学检测在疾病初期可能为阴性。聚合酶链反应分子生物学方法在急性疾病中极其重要，可实现及时诊断和治疗。
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