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使用改良布林利图分析治疗变化:历史、构建与解读

Analyzing Therapeutic Change Using Modified Brinley Plots: History, Construction, and Interpretation.

作者信息

Blampied Neville M

机构信息

University of Canterbury.

出版信息

Behav Ther. 2017 Jan;48(1):115-127. doi: 10.1016/j.beth.2016.09.002. Epub 2016 Sep 20.

Abstract

The paper reviews the history, construction, and interpretation of modified Brinley plots, a scatter plot used in therapy outcome research to compare each individual participant's scores on the same dependent variable at Time 1 (normally pretreatment baseline; x-axis), with scores at selected times during or after treatment (y-axis). Since 1965 eponymously named Brinley plots have occasionally been used in experimental psychology to display group mean data. Between 1979 and 1995 a number of clinical researchers modified Brinley plots to show individuals' data but these plots have received little subsequent use. When constructed with orthogonal axes having the same origin and scale values, little or no change over time is shown by individuals' data points lying on or closely about the diagonal (45) while the magnitude and direction of any improvement (or deterioration), outliers, and the extent of replication across cases shows via dispersion of points away from 45. Interpretation is aided by displaying reliable change boundaries, clinical cutoffs, means, variances, confidence intervals, and effect sizes directly on the graph. Modified Brinley plots are directly informative about individual change during therapy in the context of concurrent change in others in the same (or a different) condition, clearly show if outcomes are replicated and if they are clinically significant, and make nomothetic group information, notably effect sizes, directly available. They usefully complement other forms of analysis in therapy outcome research.

摘要

本文回顾了改良布林利图的历史、构建和解读。布林利图是一种散点图,用于治疗效果研究,以比较每个个体参与者在时间1(通常是治疗前基线;x轴)时在同一因变量上的得分,与治疗期间或治疗后选定时间的得分(y轴)。自1965年以来,以其命名的布林利图偶尔被用于实验心理学中展示组均值数据。在1979年至1995年期间,一些临床研究人员对布林利图进行了修改以展示个体数据,但这些图随后很少被使用。当用具有相同原点和标度值的正交轴构建时,位于对角线上或紧邻对角线(45°)的个体数据点随时间几乎没有变化,而任何改善(或恶化)的幅度和方向、异常值以及跨病例的重复程度则通过点偏离45°的离散程度来显示。通过在图上直接展示可靠变化边界、临床临界值、均值、方差、置信区间和效应量,有助于进行解读。改良布林利图能直接反映在相同(或不同)条件下其他人同时发生变化的背景下个体在治疗期间的变化,清楚地显示结果是否可重复以及是否具有临床意义,并能直接提供总体组信息,尤其是效应量。它们有效地补充了治疗效果研究中的其他分析形式。

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