Bezerra Daniel Pereira, Soares Anne Karine Nascimento, de Sousa Damião Pergentino
Gonçalo Moniz Institute, Oswaldo Cruz Foundation (IGM-FIOCRUZ-BA), Salvador, BA, Brazil.
Department of Pharmaceutical Sciences, Universidade Federal da Paraíba, 58051-970 João Pessoa, PB, Brazil.
Oxid Med Cell Longev. 2016;2016:9734816. doi: 10.1155/2016/9734816. Epub 2016 Dec 19.
Bioactive natural products play critical roles in modern drug development, especially anticancer agents. It has been widely reported that various pharmacological activities of such compounds are related to their antioxidant properties. Vanillin is a natural substance widely found in many plant species and often used in beverages, foods, cosmetics, and pharmaceutical products. Antioxidant and anticancer potential have been described for this compound. Considering the importance of vanillin in the area of human health and food and pharmaceuticals sectors, in this review, we discuss the role of vanillin on redox status and its potential contribution to the prevention and the treatment of cancer.
生物活性天然产物在现代药物开发中发挥着关键作用,尤其是抗癌药物。已有广泛报道称,此类化合物的各种药理活性与其抗氧化特性有关。香草醛是一种在许多植物物种中广泛存在的天然物质,常用于饮料、食品、化妆品和药品中。已有文献描述了该化合物的抗氧化和抗癌潜力。鉴于香草醛在人类健康以及食品和制药领域的重要性,在本综述中,我们讨论了香草醛在氧化还原状态方面的作用及其对癌症预防和治疗的潜在贡献。