Liu Huisheng, Zhao Zhanqin, Xi Xiaojian, Xue Qiao, Long Ta, Xue Yun
Laboratory of Veterinary Microbiology, College of Animal Science and Technology, Henan University of Science and Technology, Luoyang, China.
Laboratory of Medical Engineering, College of Medical Technology and Engineering, Henan University of Science and Technology, Luoyang, China.
Ir Vet J. 2017 Jan 10;70:2. doi: 10.1186/s13620-016-0080-7. eCollection 2017.
Prior to the 1990s, capsular serogroup A was the most prevalent in China, followed by serogroups B and D. Thirty years later, serogroup D became the most prevalent, followed by serogroups A and B. However, the capsular serogroups currently circulating in China remain unclear. Therefore, the aim of the present study was to provide an update on serogroups isolated from diagnostic samples collected from clinically diseased pigs in Central and Eastern China from 2011 to 2015.
Between February 2011 and October 2015, 296 isolates of were collected from 3212 pigs with clinical respiratory disease in 12 provinces of China (isolation rate of 9.2%). Of the 296 collected isolates, 146 (49.3%) were capsular type A, 141 (47.6%) were capsular type D, and one was capsular type B. (94/193; 48.7%), (76/193; 39.3%), (53/193; 27.5%), and (26/193; 13.5%) were frequently isolated together with A total of 14 toxigenic strains co-isolated with other pathogens from 32 cases of atrophic rhinitis were classified into serogroup D. The virulence of capsular type A isolates was higher than that of capsular type D isolates based on LD studies in mice.
Over the past 5 years, capsular type A was the most frequently isolated from diagnostic submissions in Central and Eastern China, followed by serogroups D and B.
20世纪90年代以前，在中国，A群是最常见的荚膜血清型，其次是B群和D群。30年后，D群成为最常见的，其次是A群和B群。然而，目前在中国流行的荚膜血清型仍不清楚。因此，本研究的目的是提供2011年至2015年在中国中部和东部地区从临床患病猪采集的诊断样本中分离出的血清型的最新情况。
2011年2月至2015年10月，从中国12个省份的3212头患有临床呼吸道疾病的猪中收集到296株分离株（分离率为9.2%）。在收集的296株分离株中，146株（49.3%）为A群荚膜型，141株（47.6%）为D群荚膜型，1株为B群荚膜型。（94/193；48.7%）、（76/193；39.3%）、（53/193；27.5%）和（26/193；13.5%）经常与A群一起分离出来。从32例萎缩性鼻炎病例中与其他病原体共分离出14株产毒素菌株，归为D群。基于小鼠的LD研究，A群荚膜型分离株的毒力高于D群荚膜型分离株。
在过去5年中，在中国中部和东部地区，从诊断样本中分离出的最常见的荚膜型是A群，其次是D群和B群。
