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意大利碘的发展之路。

The way forward in Italy for iodine.

作者信息

Olivieri Antonella, DI Cosmo Caterina, DE Angelis Simona, DA Cas Roberto, Stacchini Paolo, Pastorelli Augusto, Vitti Paolo

机构信息

Endocrinology and Metabolism Unit, Department of Cell Biology and Neuroscience, Italian National Institute of Health, Rome, Italy -

Endocrinology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.

出版信息

Minerva Med. 2017 Apr;108(2):159-168. doi: 10.23736/S0026-4806.17.04877-7. Epub 2017 Jan 12.

Abstract

Italy is dealing with iodine deficiency since ancient times. In 1848 an ad hoc committee appointed by the king of Sardinia, identified extensive areas afflicted by endemic goiter and endemic cretinism in Piedmont, Liguria and Sardinia. Since then many epidemiological studies have been conducted in our country. These showed that iodine deficiency was present not only in mountain areas but also in coastal areas. In 1972 the iodization of salt at 15 mg/kg was allowed by law and iodized salt was distributed on request to selected endemic areas. Five years later the distribution was extended to the whole country. However the sale of iodized salt was not mandatory at that time and only a small fraction of the Italian population started using iodized salt. In 1991 the content of iodine in the salt was raised to 30 mg/kg and in 2005 a nationwide salt iodization program was finally implemented. Some years later a nationwide monitoring program of iodine prophylaxis was also implemented. Since 2005 the sale of iodized salt in Italian supermarkets has increased (34% in 2006, 55% in 2012), although it has been observed that the use of iodized salt is still low in the communal eating areas and in the food industry. These data are coherent with recent epidemiological studies showing that some regions in our country are still characterized by mild iodine deficiency and a high frequency of goiter and other iodine deficiency disorders. This implies that further efforts should be made to successfully correct iodine deficiency in Italy.

摘要

意大利自古以来就面临碘缺乏问题。1848年,撒丁岛国王任命的一个特别委员会发现,皮埃蒙特、利古里亚和撒丁岛有大片地区受到地方性甲状腺肿和地方性克汀病的困扰。从那时起,我国开展了许多流行病学研究。这些研究表明,碘缺乏不仅存在于山区,也存在于沿海地区。1972年,法律允许食盐加碘量为15毫克/千克,并应要求向选定的地方性病区供应加碘盐。五年后,供应范围扩大到全国。然而,当时加碘盐的销售并非强制性的,只有一小部分意大利人口开始使用加碘盐。1991年,盐中的碘含量提高到30毫克/千克,2005年最终实施了全国性的食盐加碘计划。几年后,还实施了一项全国性的碘预防监测计划。自2005年以来,意大利超市中加碘盐的销售量有所增加(2006年为34%,2012年为55%),尽管据观察,在公共饮食区和食品工业中加碘盐的使用仍然很少。这些数据与最近的流行病学研究一致,表明我国一些地区仍然存在轻度碘缺乏以及甲状腺肿和其他碘缺乏疾病的高发病率。这意味着应进一步努力,以成功纠正意大利的碘缺乏问题。

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