Salem Hanin, Johansen Christoffer, Schmiegelow Kjeld, Winther Jeanette Falck, Wehner Peder Skov, Hasle Henrik, Rosthøj Steen, Kazak Anne E, E Bidstrup Pernille
a Danish Cancer Society Research Center , Copenhagen , Denmark.
b Department of Oncology , Finsen Centre, Rigshospitalet, The Danish Cancer Society Research Center , Copenhagen , Denmark.
Acta Oncol. 2017 Feb;56(2):367-374. doi: 10.1080/0284186X.2016.1269194. Epub 2017 Jan 12.
We developed and tested the feasibility of a manualized psychosocial intervention, FAMily-Oriented Support (FAMOS), a home-based psychosocial intervention for families of childhood cancer survivors. The aim of the intervention is to support families in adopting healthy strategies to cope with the psychological consequences of childhood cancer. The intervention is now being evaluated in a nationwide randomized controlled trial (RCT).
FAMOS is based on principles of family systems therapy and cognitive behavioral therapy, and is delivered in six sessions at home. Families were recruited from all four pediatric oncology departments in Denmark after the end of intensive cancer treatment. We evaluated the feasibility of the intervention and of a RCT design for comparing the intervention with usual care. The evaluation was conducted among families enrolled in the study by tracking procedures and parents' evaluations.
A total of 68 families (68 mothers, 60 fathers, 68 children with cancer and 73 siblings) were enrolled, with a participation rate of 62% of families. Fathers were highly represented (88% of families); also families with single parents (12%) and parents with basic education (7-12 years of primary, secondary, and grammar school education) were represented (12%). The dropout rate was 12% of families (all in the control group), and two families did not complete the intervention because of relapse. Evaluation by parents in the intervention group showed overall satisfaction with the format, timing, and content of the intervention.
The results indicate that the FAMOS intervention is feasible in terms of recruitment, retention, and acceptability. The effects of the intervention on post-traumatic stress, depression, anxiety, family functioning, and quality of life will be reported after the nationwide RCT has been completed.
我们开发并测试了一种名为“家庭导向支持（FAMOS）”的心理社会干预措施的可行性，这是一种针对儿童癌症幸存者家庭的居家心理社会干预。该干预的目的是支持家庭采用健康策略来应对儿童癌症的心理后果。目前正在一项全国性随机对照试验（RCT）中对该干预进行评估。
FAMOS基于家庭系统疗法和认知行为疗法的原则，在家中进行六次治疗。在强化癌症治疗结束后，从丹麦所有四个儿科肿瘤科室招募家庭。我们评估了该干预措施以及将其与常规护理进行比较的RCT设计的可行性。通过跟踪程序和家长评估对参与研究的家庭进行评估。
共招募了68个家庭（68位母亲、60位父亲、68名患癌儿童和73名兄弟姐妹），家庭参与率为62%。父亲的参与比例很高（占家庭的88%）；单亲家庭（12%）和接受基础教育（小学、初中和文法学校7 - 12年教育）的家长家庭（12%）也有参与。失访率为家庭的12%（均在对照组），有两个家庭因复发未完成干预。干预组家长的评估显示对干预的形式、时间安排和内容总体满意。
结果表明，FAMOS干预在招募、留存率和可接受性方面是可行的。在全国性RCT完成后，将报告该干预对创伤后应激、抑郁、焦虑、家庭功能和生活质量的影响。
