Caamaño-Isorna Francisco, Moure-Rodríguez Lucía, Doallo Sonia, Corral Montserrat, Rodriguez Holguín Socorro, Cadaveira Fernando
CIBER de Epidemiología y Salud Pública (CIBERESP), Department of Public Health, Universidade de Santiago de Compostela, Santiago de Compostela, Spain.
CIBER de Epidemiología y Salud Pública (CIBERESP), Department of Public Health, Universidade de Santiago de Compostela, Santiago de Compostela, Spain.
Accid Anal Prev. 2017 Mar;100:23-29. doi: 10.1016/j.aap.2016.12.012. Epub 2017 Jan 9.
The objective of this study is to assess the effects of Heavy Episodic Drinking (HED) on the incidence of alcohol-related injuries among university students in Spain, taking sex into consideration.
We carried out an open cohort study among college students in Spain (992 women and 371 men). HED and alcohol-related injuries were measured by question 3rd and 9th of Alcohol Use Disorders Identification Test to every participant at the ages of 18, 20, 22, 24 and 27. For data analysis we used a Multilevel Logistic Regression for repeated measures adjusting for alcohol and cannabis use.
The incidence rate of alcohol-related injuries was 0.028year for females and 0.036year for males. The multivariate analysis showed that among females a high frequency of HED and use of cannabis are risk factors for alcohol-related injuries (Odds Ratio [OR]=2.64 and OR=3.68), while being more than 23 is a protective factor (OR=0.34). For males, bivariate analysis also showed HED like risk factor (OR=4.69 and OR=2.51). Finally, the population attributable fraction for HED among females was 37.12%.
HED leads to an increase of alcohol-related injuries in both sexes and being over 23 years old acts as a protective factor among women. Our results suggest that about one third of alcohol-related injuries among women could be avoided by removing HED.
本研究的目的是评估重度暴饮（HED）对西班牙大学生酒精相关伤害发生率的影响，并考虑性别因素。
我们在西班牙大学生中开展了一项开放队列研究（992名女性和371名男性）。通过酒精使用障碍识别测试的第3题和第9题，在18岁、20岁、22岁、24岁和27岁时对每位参与者测量HED和酒精相关伤害情况。数据分析采用多水平逻辑回归重复测量法，并对酒精和大麻使用情况进行校正。
女性酒精相关伤害的发生率为0.028/年，男性为0.036/年。多变量分析显示，在女性中，HED的高频率和大麻的使用是酒精相关伤害的危险因素（优势比[OR]=2.64和OR=3.68），而年龄超过23岁是一个保护因素（OR=0.34）。对于男性，双变量分析也显示HED是危险因素（OR=4.69和OR=2.51）。最后，女性中HED的人群归因分数为37.12%。
HED导致两性酒精相关伤害增加，23岁以上对女性起到保护作用。我们的结果表明，消除HED可避免约三分之一的女性酒精相关伤害。
