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标准桃金娘油肠溶胶囊是抗生素的新替代品吗?

Is Myrtol® Standardized a New Alternative toward Antibiotics?

作者信息

Paparoupa Maria, Gillissen Adrian

机构信息

Department of Pulmonary Diseases, Klinikum Kassel, University Hospital of Southampton, Mönchebergstrasse 41-43, D-35125 Kassel, Germany.

出版信息

Pharmacogn Rev. 2016 Jul-Dec;10(20):143-146. doi: 10.4103/0973-7847.194045.

Abstract

GeloMyrtol and GeloMyrtol forte, also known as Myrtol standardized, is an herbal medical product (phytomedicine) obtained by a multistep distillation procedure from essential oils. The major biological marker of and activity of Myrtol standardized is the monoterpenes, d-limonene, 1,8-cineole, and alpha-pinene. Myrtol standardized is estimated to have antioxidative, anti-inflammatory, and antibacterial potential while many studies confirmed its secretolytic and bronchospasmolytic effects. As such, the medication is proposed to be initiated in several acute and chronic infections of the upper and lower airway system as acute and chronic rhinosinusitis, acute and chronic bronchitis, and chronic obstructive pulmonary disease. This review intends to give an insight into several prescription indications of Myrtol standardized, all involved mechanisms, and potential advantages toward antibiotic therapy, especially in cases when bacterial infection is uncertain.

摘要

吉诺通和强力吉诺通,也被称为标准桃金娘油,是一种通过多步蒸馏程序从精油中提取的草药产品(植物药)。标准桃金娘油活性的主要生物标志物是单萜类化合物、d-柠檬烯、1,8-桉叶素和α-蒎烯。据估计,标准桃金娘油具有抗氧化、抗炎和抗菌潜力,同时许多研究证实了其化痰和解支气管痉挛的作用。因此,该药物被建议用于上、下气道系统的多种急慢性感染,如急慢性鼻窦炎、急慢性支气管炎和慢性阻塞性肺疾病。本综述旨在深入探讨标准桃金娘油的几种处方适应症、所有相关机制以及相对于抗生素治疗的潜在优势,特别是在细菌感染情况不明的病例中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c101/5214559/f1be1ee69892/PRev-10-143-g001.jpg

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