Andreakou Maria I, Papadopoulos Angelos A, Panagiotakos Demosthenes B, Niakas Dimitris
Faculty of Social Sciences, Hellenic Open University, Patras, Greece.
Faculty of Social Sciences, Hellenic Open University, Patras, Greece; Second Department of Internal Medicine, Medical School, Attikon University General Hospital, Athens, Greece.
Int J Alzheimers Dis. 2016;2016:9213968. doi: 10.1155/2016/9213968. Epub 2016 Dec 19.
Alzheimer's disease (AD) dementia is a chronic neurodegenerative disorder that results in total cognitive impairment and functional decline. Family members are the most usual caregivers worldwide, resulting in a subsequent degradation of their quality of life. During November 2013-March 2014 in Athens, Greece, 155 AD patients' family caregivers' Health-Related Quality of Life and existence of depressive symptomatology were assessed. A strong negative correlation between the dimensions of HRQoL and the scores of the depression scale was revealed. AD patients' caregivers have a lower HRQoL almost in all dimensions compared to the Greek urban general population. The caregivers' social role, the existence of emotional problems, and their mental health status led to this result. Furthermore significantly important differences in caregivers' total HRQoL and depressive symptomatology were indicated in relation to their gender, hypertension existence, patient care frequency, cohabitation with the patient, disease aggravation, and economic status. Caring for relatives with AD strongly correlates with negative caregivers' HRQoL scores and adversely affects their depressive symptomatology. This negative correlation is enhanced in the later stages of the disease, in greater frequency of care, through living with a patient, in poor financial status, and with the existence of a chronic illness.
阿尔茨海默病（AD）性痴呆是一种慢性神经退行性疾病，会导致全面的认知障碍和功能衰退。在全球范围内，家庭成员是最常见的照料者，这导致他们的生活质量随后下降。2013年11月至2014年3月期间，在希腊雅典，对155名AD患者的家庭照料者的健康相关生活质量和抑郁症状的存在情况进行了评估。结果显示，健康相关生活质量各维度与抑郁量表得分之间存在强烈的负相关。与希腊城市普通人群相比，AD患者的照料者几乎在所有维度上的健康相关生活质量都较低。照料者的社会角色、情感问题的存在以及他们的心理健康状况导致了这一结果。此外，在照料者的总体健康相关生活质量和抑郁症状方面，在性别、是否患有高血压、患者照料频率、与患者同居、疾病加重情况以及经济状况等方面存在显著差异。照料患有AD的亲属与照料者负面的健康相关生活质量得分密切相关，并对他们的抑郁症状产生不利影响。这种负相关在疾病后期、照料频率更高、与患者同住、经济状况不佳以及存在慢性病的情况下会增强。
