两例在利奈唑胺治疗期间发生的严重横纹肌溶解症。
Two cases of serious rhabdomyolysis during linezolid treatment.
作者信息
Lechner Arno M, Past Eva, Porsche Ulla, Kern Jan M, Hoppe Uta, Pretsch Ingrid
机构信息
Division Medizinische Mikrobiologie, Paracelsus Medizinische Universität Salzburg, Universitätsinstitut für Medizinisch-Chemische Labordiagnostik, Muellner Hauptstrasse 48, 5020, Salzburg, Austria.
Landesapotheke Salzburg, Muellner Hauptstrasse 50, 5020, Salzburg, Austria.
出版信息
Infection. 2017 Aug;45(4):563-566. doi: 10.1007/s15010-016-0978-8. Epub 2017 Jan 12.
Linezolid is an oxazolidinone antibiotic with activity against gram-positive organisms, particularly methicillin-resistant Staphylococcus aureus (MRSA). To the best of our knowledge, there are only two case reports on rhabdomyolysis in patients treated with linezolid. Here, we describe two cases of serious rhabdomyolysis: one in a patient with septic community-acquired (CA)-MRSA pneumonia and a second case in a patient with suspected catheter-related blood stream infection.
利奈唑胺是一种恶唑烷酮类抗生素，对革兰氏阳性菌具有活性，尤其是耐甲氧西林金黄色葡萄球菌（MRSA）。据我们所知，关于使用利奈唑胺治疗的患者发生横纹肌溶解症的病例报告仅有两例。在此，我们描述两例严重横纹肌溶解症病例：一例发生在患有社区获得性（CA）-MRSA败血症肺炎的患者中，另一例发生在疑似导管相关血流感染的患者中。
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