Jin Yuanxiang, Wu Sisheng, Zeng Zhaoyang, Fu Zhengwei
College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou 310032, China.
College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou 310032, China.
Environ Pollut. 2017 Mar;222:1-9. doi: 10.1016/j.envpol.2016.11.045. Epub 2017 Jan 11.
Environmental pollutants have become an increasingly common health hazard in the last several decades. Recently, a number of studies have demonstrated the profound relationship between gut microbiota and our health. Gut microbiota are very sensitive to drugs, diet, and even environmental pollutants. In this review, we discuss the possible effects of environmental pollutants including antibiotics, heavy metals, persistent organic pollutants, pesticides, nanomaterials, and food additives on gut microbiota and their subsequent effects on health. We emphasize that gut microbiota are also essential for the toxicity evaluation of environmental pollution. In the future, more studies should focus on the relationship between environmental pollution, gut microbiota, and human health.
在过去几十年中，环境污染物已成为日益常见的健康危害。最近，多项研究表明肠道微生物群与我们的健康之间存在着深远的关系。肠道微生物群对药物、饮食甚至环境污染物都非常敏感。在这篇综述中，我们讨论了包括抗生素、重金属、持久性有机污染物、农药、纳米材料和食品添加剂在内的环境污染物对肠道微生物群的可能影响及其对健康的后续影响。我们强调肠道微生物群对于环境污染的毒性评估也至关重要。未来，更多的研究应聚焦于环境污染、肠道微生物群和人类健康之间的关系。
