Laboratorio de Higiene Inspección y Control de Alimentos. Dpto. de Química Analítica, Nutrición y Bromatología, Universidade de Santiago de Compostela, 27002, Lugo, Spain.
J Physiol Biochem. 2018 Feb;74(1):69-83. doi: 10.1007/s13105-017-0564-2. Epub 2017 May 9.
Gut bacteria play an important role in several metabolic processes and human diseases, such as obesity and accompanying co-morbidities, such as fatty liver disease, insulin resistance/diabetes, and cardiovascular events. Among other factors, dietary patterns, probiotics, prebiotics, synbiotics, antibiotics, and non-dietary factors, such as stress, age, exercise, and climatic conditions, can dramatically impact the human gut microbiota equilibrium and diversity. However, the effect of minor food constituents, including food additives and trace contaminants, on human gut microbiota has received less attention. Consequently, the present review aimed to provide an objective perspective of the current knowledge regarding the impacts of minor food constituents on human gut microbiota and consequently, on human health.
肠道细菌在几种代谢过程和人类疾病中发挥着重要作用，如肥胖症以及伴随的合并症，如脂肪肝疾病、胰岛素抵抗/糖尿病和心血管事件。除其他因素外，饮食模式、益生菌、益生元、合生菌、抗生素和非饮食因素，如压力、年龄、运动和气候条件，都可以显著影响人类肠道微生物群的平衡和多样性。然而，包括食品添加剂和痕量污染物在内的少量食物成分对人类肠道微生物群的影响受到的关注较少。因此，本综述旨在客观地介绍目前关于少量食物成分对人类肠道微生物群的影响以及对人类健康的影响的知识。
