Understanding histone deacetylation in Huntington's disease.
作者信息
Valor Luis Miguel
机构信息
Unidad de Investigación, Hospital Universitario Puerta del Mar, Cádiz, Spain.
出版信息
Oncotarget. 2017 Jan 24;8(4):5660-5661. doi: 10.18632/oncotarget.13924.
Abstract
摘要
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本文引用的文献
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Specific promoter deacetylation of histone H3 is conserved across mouse models of Huntington's disease in the absence of bulk changes.在无整体变化的情况下，组蛋白H3的特定启动子去乙酰化在亨廷顿舞蹈病小鼠模型中是保守的。
Neurobiol Dis. 2016 May;89:190-201. doi: 10.1016/j.nbd.2016.02.004. Epub 2016 Feb 3.
2
The Role of H3K4me3 in Transcriptional Regulation Is Altered in Huntington's Disease.H3K4me3在转录调控中的作用在亨廷顿舞蹈病中发生改变。
PLoS One. 2015 Dec 4;10(12):e0144398. doi: 10.1371/journal.pone.0144398. eCollection 2015.
3
Epigenetic-based therapies in the preclinical and clinical treatment of Huntington's disease.基于表观遗传学的疗法在亨廷顿舞蹈症临床前及临床治疗中的应用
Int J Biochem Cell Biol. 2015 Oct;67:45-8. doi: 10.1016/j.biocel.2015.04.009. Epub 2015 Apr 30.
4
Neuronal identity genes regulated by super-enhancers are preferentially down-regulated in the striatum of Huntington's disease mice.由超级增强子调控的神经元身份基因在亨廷顿病小鼠的纹状体中优先下调。
Hum Mol Genet. 2015 Jun 15;24(12):3481-96. doi: 10.1093/hmg/ddv099. Epub 2015 Mar 17.
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Can changes in histone acetylation contribute to memory formation?组蛋白乙酰化的变化能否有助于记忆的形成？
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