靶向炎症中的多巴胺受体D3信号通路。 - Suppr

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超能文献

Targeting dopamine receptor D3 signalling in inflammation.

作者信息

Pacheco Rodrigo

机构信息

Departamento de Ciencias Biológicas, Facultad de Ciencias Biológicas, Universidad Andres Bello, Santiago, Chile.

Laboratorio de Neuroinmunología, Fundación Ciencia & Vida, Ñuñoa, Santiago, Chile.

出版信息

Oncotarget. 2017 Jan 31;8(5):7224-7225. doi: 10.18632/oncotarget.14601.

DOI:10.18632/oncotarget.14601

PMID:28086229

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5352314/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e526/5352314/a03de2f86eab/oncotarget-08-7224-g001.jpg

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本文引用的文献

Inhibition of dopamine receptor D3 signaling in dendritic cells increases antigen cross-presentation to CD8 T-cells favoring anti-tumor immunity.抑制树突状细胞中的多巴胺受体D3信号传导可增强抗原向CD8 T细胞的交叉呈递，从而促进抗肿瘤免疫。

J Neuroimmunol. 2017 Feb 15;303:99-107. doi: 10.1016/j.jneuroim.2016.12.014. Epub 2017 Jan 2.

Pharmacologic antagonism of dopamine receptor D3 attenuates neurodegeneration and motor impairment in a mouse model of Parkinson's disease.多巴胺受体D3的药理拮抗作用可减轻帕金森病小鼠模型中的神经退行性变和运动障碍。

Neuropharmacology. 2017 Feb;113(Pt A):110-123. doi: 10.1016/j.neuropharm.2016.09.028. Epub 2016 Sep 28.

Dopamine Receptor D3 Signaling on CD4+ T Cells Favors Th1- and Th17-Mediated Immunity.CD4+ T细胞上的多巴胺受体D3信号传导有利于Th1和Th17介导的免疫反应。

J Immunol. 2016 May 15;196(10):4143-9. doi: 10.4049/jimmunol.1502420. Epub 2016 Apr 18.

Dopamine controls systemic inflammation through inhibition of NLRP3 inflammasome.多巴胺通过抑制 NLRP3 炎性小体来控制全身炎症。

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The dopaminergic system in autoimmune diseases.自身免疫性疾病中的多巴胺能系统。

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