Oral Pathology Laboratory, Dental School, National Autonomous University of México, México City, México.
Oral Dis. 2010 Mar;16(2):185-7. doi: 10.1111/j.1601-0825.2009.01625.x. Epub 2009 Sep 11.
The aim of this study was to establish the impact of the redefinition and reclassification of odontogenic keratocyst (OKC) as a tumour on the prevalence of odontogenic tumours (OT).
We revised 15 435 files of a teaching head and neck histopathology service in the time period from January 1981 to December 2008 and 478 cases of OT were selected. The 342 cases from 1981 to 2004 were classified according 1992 to the World Health Organization (WHO)-classification (excluding keratocystic OT) while the 136 cases from 2005 onwards were classified according to the 2005 WHO-classification (including keratocystic OT). Age and gender were obtained from medical records. The frequency distribution and prevalence of OT from each periods of time were compared. A chi-square test was performed (P < 0.05 95% confidence interval).
The prevalence of OT increases 92% in the 2005-2008 period; from 2.6% (1981-2004 period) to 5% (2005-2008 period) (P 0.000).The most frequent OT in the 1981-2004 period was odontoma (45% of all OT) while in the 2005-2008 period was Keratocystic Odontogenicv Tumour (38.9%).
The redefinition of OKC as a tumour produced an increase in the frequency and prevalence of OT.
本研究旨在确定将牙源性角化囊肿（OKC）重新定义和重新分类为肿瘤对牙源性肿瘤（OT）患病率的影响。
我们复习了 1981 年 1 月至 2008 年 12 月期间一家教学头颈部组织病理学服务机构的 15435 份档案，选择了 478 例 OT 病例。1981 年至 2004 年的 342 例病例根据 1992 年世界卫生组织（WHO）分类（不包括角化囊性 OT）进行分类，而 2005 年及以后的 136 例病例则根据 2005 年 WHO 分类（包括角化囊性 OT）进行分类。从病历中获取年龄和性别。比较各时间段 OT 的频率分布和患病率。采用卡方检验（P<0.05，95%置信区间）。
2005-2008 年期间，OT 的患病率增加了 92%；从 1981-2004 年期间的 2.6%上升至 2005-2008 年期间的 5%（P<0.000）。1981-2004 年期间最常见的 OT 是牙瘤（所有 OT 的 45%），而 2005-2008 年期间最常见的是角化囊性牙源性肿瘤（38.9%）。
将 OKC 重新定义为肿瘤导致 OT 的频率和患病率增加。
