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旅行者在阿尔及利亚接触到一只确诊的狂犬病狗,出现家族性聚集现象。

Familial cluster of exposure to a confirmed rabid dog in travelers to Algeria.

机构信息

Institut Hospitalo-Universitaire Méditerranée Infection, 13005, Marseille, France.

Institut Hospitalo-Universitaire Méditerranée Infection, 13005, Marseille, France; Aix Marseille Université, URMITE, UM63, CNRS 7278, IRD 198, INSERM 1095, Marseille, France.

出版信息

Travel Med Infect Dis. 2017 Mar-Apr;16:46-48. doi: 10.1016/j.tmaid.2017.01.001. Epub 2017 Jan 9.

Abstract

A 10 person-family originating from Algeria traveled in rural Algeria for the purpose of visiting friends and relatives without seeking pre-travel advice, did not received pre-travel rabies immunization, and were exposed to a confirmed rabid dog including 8 within less than 4 days of arrival. Three received suckling mouse brain rabies vaccine although WHO strongly recommends that its production and administration be discontinued and seven received insufficient doses of equine rabies immune globulin abroad. Rabies treatment was completed on returning to France. This reports underline the fact that travelers visiting friends and relatives in dog rabies endemic country are at high risk of rabies exposure and unaware of such a risk in most instances. Rabies risk warning should be reinforced and rabies pre-exposure vaccination should be considered in all individuals traveling to North Africa (and to sub-Saharan Africa) whatever the duration of stay.

摘要

一个 10 人的家庭,来自阿尔及利亚,为了探亲访友而前往阿尔及利亚农村旅行,没有寻求旅行前咨询,没有接受旅行前狂犬病免疫接种,接触了一只确诊的狂犬病狗,其中 8 人在抵达后不到 4 天内接触。尽管世界卫生组织强烈建议停止生产和使用这种疫苗,但有 3 人接种了幼鼠脑狂犬病疫苗,有 7 人在国外接种了不足剂量的马用狂犬病免疫球蛋白。在返回法国后完成了狂犬病治疗。本报告强调了一个事实,即前往狂犬病流行国家探亲访友的旅行者面临很高的狂犬病暴露风险,而且大多数情况下都不知道这种风险。应该加强狂犬病风险警告,并考虑对所有前往北非(以及撒哈拉以南非洲)的旅行者进行狂犬病暴露前疫苗接种,无论逗留时间长短。

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